Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	5-Ethynyl Nicotine	(S)-2	Efficacy	=	52	%	ALA3365585			%	Homo sapiens
2.	5-Ethynyl Nicotine	(S)-2	Efficacy	=	49	%	ALA3365584			%	Homo sapiens
3.	5-Ethynyl Nicotine	(S)-2	EC50	=	1.8	uM	ALA3363168	5.75		nM	Homo sapiens
4.	5-Ethynyl Nicotine	(S)-2	EC50	=	23	uM	ALA3363169	4.64		nM	Homo sapiens
5.	5-Ethynyl Nicotine	(S)-2	pIC50	<	4.7		ALA4651403		No. Measurements = 1	nM	Severe acute respiratory syndrome coronavirus 2
6.	5-Ethynyl Nicotine	(S)-2	IC50	>	0	M	ALA4651403		No. Measurements = 1	nM	Severe acute respiratory syndrome coronavirus 2
7.	5-Ethynyl Nicotine	(S)-2	inhibition	=	2.66	%	ALA4808150			%	Homo sapiens
8.	5-Ethynyl Nicotine	(S)-2	inhibition	=	18.91	%	ALA4808149			%	Homo sapiens
9.	5-Ethynyl Nicotine	(S)-2	Rmax	=	26	%	ALA826916			%	Homo sapiens
10.	5-Ethynyl Nicotine	(S)-2	EC50	=	2	uM	ALA830028	5.70		nM	Homo sapiens
11.	5-Ethynyl Nicotine	(S)-2	Rmax	=	52	%	ALA826914			%	Homo sapiens
12.	5-Ethynyl Nicotine	(S)-2	EC50	=	10	uM	ALA830026	5.00		nM	Homo sapiens
13.	5-Ethynyl Nicotine	(S)-2	Rmax	=	49	%	ALA826912			%	Homo sapiens
14.	5-Ethynyl Nicotine	(S)-2	EC50	=	3.2	uM	ALA830024	5.50		nM	Homo sapiens
15.	5-Ethynyl Nicotine	(S)-2	Rmax	=	49	%	ALA826915			%	Homo sapiens
16.	5-Ethynyl Nicotine	(S)-2	EC50	=	0.32	uM	ALA830027	6.50		nM	Homo sapiens
17.	5-Ethynyl Nicotine	(S)-2	EC50	>	10	uM	ALA830005			nM	Homo sapiens
18.	5-Ethynyl Nicotine	(S)-2	EC50	=	3.2	uM	ALA830025	5.50		nM	Homo sapiens
19.	5-Ethynyl Nicotine	(S)-2	EC50		0	uM	ALA751145		Not Determined	nM	Homo sapiens
20.	5-Ethynyl Nicotine	(S)-2	EC50	=	49	uM	ALA751478	4.31		nM	Homo sapiens