# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3357560 | alpha-hdroxytropolone | INH | = | 100 | % | ALA3385135 | % | ||||
2. | ALA3357560 | alpha-hdroxytropolone | INH | = | 78 | % | ALA3385136 | % | ||||
3. | ALA3357560 | alpha-hdroxytropolone | INH | = | 8 | % | ALA3385137 | % | ||||
4. | ALA3357560 | alpha-hdroxytropolone | pIC50 | = | 8 | ALA4158866 | 8.00 | nM | ||||
5. | ALA3357560 | alpha-hdroxytropolone | INH | = | 58 | % | ALA4158877 | % | Homo sapiens | |||
6. | ALA3357560 | alpha-hdroxytropolone | INH | = | 92 | % | ALA4158869 | % | ||||
7. | ALA3357560 | alpha-hdroxytropolone | INH | = | 92 | % | ALA4158868 | % | Homo sapiens | |||
8. | ALA3357560 | alpha-hdroxytropolone | INH | = | 95 | % | ALA4158867 | % | ||||
9. | ALA3357560 | alpha-hdroxytropolone | IC50 | = | 11 | nM | ALA4158866 | 7.96 | nM | |||
10. | ALA3357560 | alpha-hdroxytropolone | INH | = | 8 | % | ALA3590919 | % | ||||
11. | ALA3357560 | alpha-hdroxytropolone | INH | = | 78 | % | ALA3590918 | % | ||||
12. | ALA3357560 | alpha-hdroxytropolone | INH | = | 100 | % | ALA3592964 | % | ||||
13. | ALA3357560 | alpha-hdroxytropolone | Ki | = | 23 | uM | ALA3592963 | 4.64 | nM | |||
14. | ALA3357560 | alpha-hdroxytropolone | Ki | = | 16 | uM | ALA3592962 | 4.80 | nM | |||
15. | ALA3357560 | alpha-hdroxytropolone | IC50 | = | 2 | uM | ALA3593060 | 5.70 | nM | Homo sapiens | ||
16. | ALA3357560 | alpha-hdroxytropolone | IC50 | = | 15 | uM | ALA3593059 | 4.82 | nM | |||
17. | ALA3357560 | alpha-hdroxytropolone | IC50 | = | 75 | uM | ALA3593058 | 4.12 | nM | |||
18. | ALA3357560 | alpha-hdroxytropolone | IC50 | = | 1.7 | uM | ALA3593054 | 5.77 | nM | Homo sapiens | ||
19. | ALA3357560 | alpha-hdroxytropolone | IC50 | = | 8.7 | uM | ALA3593053 | 5.06 | nM | Plasmodium falciparum | ||
20. | ALA3357560 | alpha-hdroxytropolone | IC50 | = | 6.4 | uM | ALA3593052 | 5.19 | nM | Plasmodium falciparum |