| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3357685 | 6 | MCD | = | 6 | mg kg-1 | ALA3387697 | mg kg-1 | Trypanosoma brucei rhodesiense | |||
| 2. | ALA3357685 | 6 | F | = | 93 | % | ALA3387696 | % | Mus musculus | |||
| 3. | ALA3357685 | 6 | AUC | = | 3400 | microg/min/ml | ALA3387695 | ng.hr.mL-1 | Mus musculus | |||
| 4. | ALA3357685 | 6 | FC | = | 2 | ALA3387698 | Trypanosoma brucei rhodesiense | |||||
| 5. | ALA3357685 | 6 | Selectivity Index | = | 10 | ALA3387694 | ||||||
| 6. | ALA3357685 | 6 | BBR | < | 0.1 | ALA3387689 | Mus musculus | |||||
| 7. | ALA3357685 | 6 | EC50 | = | 0.09 | uM | ALA3387687 | 7.05 | nM | Homo sapiens | ||
| 8. | ALA3357685 | 6 | EC50 | = | 0 | uM | ALA3387686 | 9.40 | nM | Trypanosoma brucei | ||
| 9. | ALA3357685 | 6 | IC50 | = | 0.004 | uM | ALA3387685 | 8.40 | nM | Homo sapiens | ||
| 10. | ALA3357685 | 6 | IC50 | = | 0.002 | uM | ALA3387684 | 8.70 | nM | |||
| 11. | ALA3357685 | 6 | IC50 | = | 12 | nM | ALA4194483 | 7.92 | nM | |||
| 12. | ALA3357685 | 6 | MIC | = | 925 | uM | ALA4194481 | nM | Aspergillus fumigatus | |||
| 13. | ALA3357685 | 6 | IC50 | = | 12 | nM | ALA4185534 | 7.92 | nM | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSCA1100) (Aspergillus fumigatus) | ||
| 14. | ALA3357685 | 6 | IC50 | = | 3 | nM | ALA3887334 | 8.52 | 333516 | nM | Homo sapiens | |
| 15. | ALA3357685 | 6 | IC50 | = | 1 | nM | ALA3887333 | 9.00 | 333259 | nM | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) |
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