# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3358156 | 11 | Drug degradation | = | 13 | % | ALA3389535 | % | ||||
2. | ALA3358156 | 11 | Drug degradation | = | 17 | % | ALA3389534 | % | ||||
3. | ALA3358156 | 11 | INH | < | 5 | % | ALA3389533 | % | Homo sapiens | |||
4. | ALA3358156 | 11 | INH | < | 5 | % | ALA3389532 | % | Homo sapiens | |||
5. | ALA3358156 | 11 | INH | < | 5 | % | ALA3388968 | % | Homo sapiens | |||
6. | ALA3358156 | 11 | F | = | 58 | % | ALA3388967 | % | Rattus norvegicus | |||
7. | ALA3358156 | 11 | CL | = | 13 | ml/min.kg | ALA3388966 | mL.min-1.kg-1 | Rattus norvegicus | |||
8. | ALA3358156 | 11 | t1/2 | = | 4.2 | hr | ALA3388965 | hr | Rattus norvegicus | |||
9. | ALA3358156 | 11 | Tmax | = | 0.33 | hr | ALA3388964 | hr | Rattus norvegicus | |||
10. | ALA3358156 | 11 | Cmax | = | 4100 | ng/ml | ALA3388963 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
11. | ALA3358156 | 11 | AUC | = | 8100 | ng.hr/ml | ALA3388962 | ng.hr.mL-1 | Rattus norvegicus | |||
12. | ALA3358156 | 11 | ED50 | = | 75 | mg kg-1 | ALA3388960 | mg.kg-1 | Rattus norvegicus | |||
13. | ALA3358156 | 11 | Cp | = | 80 | ng/ml | ALA3388959 | ng/ml | Rattus norvegicus | |||
14. | ALA3358156 | 11 | Cp | = | 2200 | ng/ml | ALA3388958 | ng/ml | Rattus norvegicus | |||
15. | ALA3358156 | 11 | IC50 | 0 | ALA3388957 | Not Determined | Homo sapiens | |||||
16. | ALA3358156 | 11 | IC50 | > | 100000 | nM | ALA3388956 | nM | Homo sapiens | |||
17. | ALA3358156 | 11 | IC50 | = | 4200 | nM | ALA3388955 | 5.38 | nM | Homo sapiens | ||
18. | ALA3358156 | 11 | IC50 | = | 38000 | nM | ALA3388954 | 4.42 | nM | Homo sapiens | ||
19. | ALA3358156 | 11 | IC50 | = | 7500 | nM | ALA3388953 | 5.12 | nM | Homo sapiens | ||
20. | ALA3358156 | 11 | IC50 | = | 110 | nM | ALA3388952 | 6.96 | nM | Homo sapiens |