# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3358158 | 13 | Drug degradation | = | 7 | % | ALA3389535 | % | ||||
2. | ALA3358158 | 13 | Drug degradation | < | 5 | % | ALA3389534 | % | ||||
3. | ALA3358158 | 13 | INH | < | 5 | % | ALA3389533 | % | Homo sapiens | |||
4. | ALA3358158 | 13 | INH | < | 5 | % | ALA3389532 | % | Homo sapiens | |||
5. | ALA3358158 | 13 | INH | < | 5 | % | ALA3388968 | % | Homo sapiens | |||
6. | ALA3358158 | 13 | F | = | 25 | % | ALA3388967 | % | Rattus norvegicus | |||
7. | ALA3358158 | 13 | CL | = | 4.8 | ml/min.kg | ALA3388966 | mL.min-1.kg-1 | Rattus norvegicus | |||
8. | ALA3358158 | 13 | t1/2 | = | 4.3 | hr | ALA3388965 | hr | Rattus norvegicus | |||
9. | ALA3358158 | 13 | Tmax | = | 1.6 | hr | ALA3388964 | hr | Rattus norvegicus | |||
10. | ALA3358158 | 13 | Cmax | = | 3200 | ng/ml | ALA3388963 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
11. | ALA3358158 | 13 | AUC | = | 8500 | ng.hr/ml | ALA3388962 | ng.hr.mL-1 | Rattus norvegicus | |||
12. | ALA3358158 | 13 | INH | 0 | ALA3388961 | Dose-dependent effect | % | Rattus norvegicus | ||||
13. | ALA3358158 | 13 | ED50 | = | 30 | mg kg-1 | ALA3388960 | mg.kg-1 | Rattus norvegicus | |||
14. | ALA3358158 | 13 | Cp | = | 90 | ng/ml | ALA3388959 | ng/ml | Rattus norvegicus | |||
15. | ALA3358158 | 13 | Cp | = | 1100 | ng/ml | ALA3388958 | ng/ml | Rattus norvegicus | |||
16. | ALA3358158 | 13 | IC50 | = | 10000 | nM | ALA3388957 | 5.00 | nM | Homo sapiens | ||
17. | ALA3358158 | 13 | IC50 | = | 86000 | nM | ALA3388956 | 4.07 | nM | Homo sapiens | ||
18. | ALA3358158 | 13 | IC50 | = | 30000 | nM | ALA3388955 | 4.52 | nM | Homo sapiens | ||
19. | ALA3358158 | 13 | IC50 | = | 69000 | nM | ALA3388954 | 4.16 | nM | Homo sapiens | ||
20. | ALA3358158 | 13 | IC50 | = | 11000 | nM | ALA3388953 | 4.96 | nM | Homo sapiens |