| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  AZ82 | 39, AZ82 | Cmax | = | 38000 | ng/ml | ALA3382511 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 2. | AZ82 | 39, AZ82 | AUC | = | 120000 | ng.hr/ml | ALA3382507 | ng.hr.mL-1 | Mus musculus | |||
| 3. | AZ82 | 39, AZ82 | t1/2 | = | 3.3 | hr | ALA3382510 | hr | Mus musculus | |||
| 4. | AZ82 | 39, AZ82 | Cmax | = | 1000 | ng/ml | ALA3382509 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 5. | AZ82 | 39, AZ82 | AUC | = | 5600 | ng.hr/ml | ALA3382508 | ng.hr.mL-1 | Mus musculus | |||
| 6. | AZ82 | 39, AZ82 | Cmax | = | 67 | ng/ml | ALA3382506 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 7. | AZ82 | 39, AZ82 | AUC | = | 211 | ng.hr/ml | ALA3382505 | ng.hr.mL-1 | Mus musculus | |||
| 8. | AZ82 | 39, AZ82 | Ratio | > | 120 | ALA3382504 | ||||||
| 9. | AZ82 | 39, AZ82 | t1/2 | = | 8.4 | hr | ALA3382503 | hr | Rattus norvegicus | |||
| 10. | AZ82 | 39, AZ82 | Vd | = | 1.3 | L/Kg | ALA3382502 | L.kg-1 | Rattus norvegicus | |||
| 11. | AZ82 | 39, AZ82 | CL | = | 0.6 | L/hr/kg | ALA3382501 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 12. | AZ82 | 39, AZ82 | IC50 | = | 0.31 | uM | ALA3390316 | 6.51 | nM | Homo sapiens | ||
| 13. | AZ82 | 39, AZ82 | solubility | = | 5.5 | uM | ALA3390317 | nM | ||||
| 14. | AZ82 | 39, AZ82 | Fu | < | 1 | % | ALA3390318 | Homo sapiens | ||||
| 15. | AZ82 | 39, AZ82 | INH | 0 | ALA3390319 | Active | % | Homo sapiens | ||||
| 16. | AZ82 | 39, AZ82 | INH | 0 | ALA3382499 | Not Active | % | Homo sapiens | ||||
| 17. | AZ82 | 39, AZ82 | INH | 0 | ALA3382500 | Active | % | Homo sapiens | ||||
| 18. | AZ82 | 39, AZ82 | INH | 0 | ALA4616904 | Dose-dependent effect | % |
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