Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA3359522	24	IC50	=	390	nM	ALA3380172	6.41		nM
2.	ALA3359522	24	IC50	=	8.5	uM	ALA3380167	5.07		nM	Homo sapiens
3.	ALA3359522	24	Activity		0		ALA3380166		Non-toxic		Rattus norvegicus
4.	ALA3359522	24	Activity		0		ALA3380165		Not Active		Homo sapiens
5.	ALA3359522	24	IC50	=	10.4	ng/ml	ALA3380156			ug.mL-1	Rattus norvegicus
6.	ALA3359522	24	BPR	=	0.09		ALA3380155
7.	ALA3359522	24	F	=	76.4	%	ALA3380154			%	Rattus norvegicus
8.	ALA3359522	24	beta t1/2	=	3.44	hr	ALA3380153			hr	Rattus norvegicus
9.	ALA3359522	24	AUC	=	4.21	ug.hr/ml	ALA3380152			ng.hr.mL-1	Rattus norvegicus
10.	ALA3359522	24	Tmax	=	4	hr	ALA3380151			hr	Rattus norvegicus
11.	ALA3359522	24	Cmax	=	0.618	ug ml-1	ALA3380150		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
12.	ALA3359522	24	Vdss	=	0.9	L/Kg	ALA3380149			L.kg-1	Rattus norvegicus
13.	ALA3359522	24	CL	=	0.192	L/hr/kg	ALA3380148			mL.min-1.kg-1	Rattus norvegicus
14.	ALA3359522	24	Emax	=	96	%	ALA3380164			%	Macaca mulatta
15.	ALA3359522	24	EC50	=	0.038	nM	ALA3380163	10.42		nM	Macaca mulatta
16.	ALA3359522	24	Emax	=	66	%	ALA3380162			%	Canis lupus familiaris
17.	ALA3359522	24	EC50	=	0.049	nM	ALA3380161	10.31		nM	Canis lupus familiaris
18.	ALA3359522	24	Emax	=	93	%	ALA3380160			%	Rattus norvegicus
19.	ALA3359522	24	EC50	=	0.072	nM	ALA3380159	10.14		nM	Rattus norvegicus
20.	ALA3359522	24	Emax	=	104	%	ALA3380158			%	Mus musculus