# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3359523 | 25 | solubility | > | 100 | mg/ml | ALA3380830 | ug.mL-1 | ||||
2. | ALA3359523 | 25 | solubility | < | 0.001 | mg/ml | ALA3380829 | ug.mL-1 | ||||
3. | ALA3359523 | 25 | EC50 | = | 8.9 | nM | ALA3380828 | 8.05 | nM | |||
4. | ALA3359523 | 25 | Activity | 0 | ALA3380827 | Not Active | Mus musculus | |||||
5. | ALA3359523 | 25 | Activity | 0 | ALA3380826 | Dose-dependent effect | Mus musculus | |||||
6. | ALA3359523 | 25 | Activity | 0 | ALA3380825 | Active | Mus musculus | |||||
7. | ALA3359523 | 25 | IC50 | = | 18.3 | ng/ml | ALA3380824 | ug.mL-1 | Mus musculus | |||
8. | ALA3359523 | 25 | Cmax | = | 72.2 | ug ml-1 | ALA3380823 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
9. | ALA3359523 | 25 | BPR | = | 1.61 | ALA3380822 | ||||||
10. | ALA3359523 | 25 | Drug uptake | = | 568 | ng/ml | ALA3380174 | ng/ml | Rattus norvegicus | |||
11. | ALA3359523 | 25 | Cp | = | 352 | ng/ml | ALA3380173 | ng/ml | Rattus norvegicus | |||
12. | ALA3359523 | 25 | IC50 | 0 | ALA3380172 | Not Active | ||||||
13. | ALA3359523 | 25 | IC50 | > | 50 | uM | ALA3380171 | nM | Homo sapiens | |||
14. | ALA3359523 | 25 | IC50 | > | 50 | uM | ALA3380170 | nM | Homo sapiens | |||
15. | ALA3359523 | 25 | IC50 | > | 50 | uM | ALA3380169 | nM | Homo sapiens | |||
16. | ALA3359523 | 25 | IC50 | > | 50 | uM | ALA3380168 | nM | Homo sapiens | |||
17. | ALA3359523 | 25 | IC50 | > | 50 | uM | ALA3380167 | nM | Homo sapiens | |||
18. | ALA3359523 | 25 | Activity | 0 | ALA3380166 | Non-toxic | Rattus norvegicus | |||||
19. | ALA3359523 | 25 | Activity | 0 | ALA3380165 | Not Active | Homo sapiens | |||||
20. | ALA3359523 | 25 | IC50 | = | 25.4 | ng/ml | ALA3380156 | ug.mL-1 | Rattus norvegicus |