# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MMAF | 6-OMe, MMAF-OMe | Activity | 0 | ALA4845503 | Not Active | ||||||
2. | MMAF | 6-OMe, MMAF-OMe | IC50 | = | 5.3 | nM | ALA4845498 | 8.28 | nM | Homo sapiens | ||
3. | MMAF | 6-OMe, MMAF-OMe | IC50 | = | 8.8 | nM | ALA4845497 | 8.06 | nM | Homo sapiens | ||
4. | MMAF | 6-OMe, MMAF-OMe | IC50 | 0 | ALA4845496 | Not Active | Homo sapiens | |||||
5. | MMAF | 6-OMe, MMAF-OMe | INH | 0 | ALA4845495 | Active | % | Homo sapiens | ||||
6. | MMAF | 6-OMe, MMAF-OMe | Activity | = | 9.66 | % | ALA4845494 | % | Homo sapiens | |||
7. | MMAF | 6-OMe, MMAF-OMe | Activity | = | 30.88 | % | ALA4845493 | % | Homo sapiens | |||
8. | MMAF | 6-OMe, MMAF-OMe | Activity | = | 16.11 | % | ALA4845492 | % | Homo sapiens | |||
9. | MMAF | 6-OMe, MMAF-OMe | Activity | = | 32.79 | % | ALA4845491 | % | Homo sapiens | |||
10. | MMAF | 6-OMe, MMAF-OMe | INH | 0 | ALA4845490 | Dose-Dependent Effect | % | Homo sapiens | ||||
11. | MMAF | 6-OMe, MMAF-OMe | GI50 | = | 0.24 | nM | ALA3390352 | nM | Homo sapiens | |||
12. | MMAF | 6-OMe, MMAF-OMe | GI50 | = | 0.44 | nM | ALA3390354 | nM | Homo sapiens | |||
13. | MMAF | 6-OMe, MMAF-OMe | GI50 | = | 0.21 | nM | ALA3390353 | nM | Homo sapiens | |||
14. | MMAF | 6-OMe, MMAF-OMe | IC50 | = | 137 | nM | ALA5152394 | 6.86 | nM | Homo sapiens | ||
15. | MMAF | 6-OMe, MMAF-OMe | IC50 | = | 2.88 | uM | ALA5152393 | 5.54 | nM | Homo sapiens | ||
16. | MMAF | 6-OMe, MMAF-OMe | IC50 | = | 10 | nM | ALA5152383 | 8.00 | nM | Homo sapiens | ||
17. | MMAF | 6-OMe, MMAF-OMe | IC50 | = | 105 | nM | ALA5152380 | 6.98 | nM | Homo sapiens | ||
18. | MMAF | 6-OMe, MMAF-OMe | MTD | = | 1 | mg kg-1 | ALA5152378 | mg kg-1 |