# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3398482 | 27e | MED | = | 3 | mg kg-1 | ALA4624060 | mg kg-1 | Rattus norvegicus | |||
2. | ALA3398482 | 27e | t1/2 | = | 0.412 | hr | ALA4624059 | hr | ||||
3. | ALA3398482 | 27e | Kb | = | 6.06 | nM | ALA4624050 | nM | Rattus norvegicus | |||
4. | ALA3398482 | 27e | Kb | = | 5.08 | nM | ALA4624049 | nM | Rattus norvegicus | |||
5. | ALA3398482 | 27e | t1/2 | = | 1.07 | hr | ALA4624038 | hr | ||||
6. | ALA3398482 | 27e | CL | = | 598 | ml/hr.kg | ALA4624036 | mL.min-1.kg-1 | ||||
7. | ALA3398482 | 27e | Vd | = | 745 | ml/kg | ALA4624034 | L.kg-1 | ||||
8. | ALA3398482 | 27e | logD | = | 2.53 | ALA4624032 | ||||||
9. | ALA3398482 | 27e | IC50 | = | 38.7 | nM | ALA4624029 | 7.41 | nM | Homo sapiens | ||
10. | ALA3398482 | 27e | IC50 | = | 20.6 | nM | ALA4624028 | 7.69 | nM | Homo sapiens | ||
11. | ALA3398482 | 27e | Vd | = | 1710 | ml/kg | ALA4624057 | L.kg-1 | ||||
12. | ALA3398482 | 27e | CL | = | 3960 | ml/hr/kg | ALA4624058 | mL.min-1.kg-1 | ||||
13. | ALA3398482 | 27e | Activity | = | 66 | % | ALA3399383 | % | Homo sapiens | |||
14. | ALA3398482 | 27e | Kb | = | 6.06 | nM | ALA3399382 | nM | Rattus norvegicus | |||
15. | ALA3398482 | 27e | Kb | = | 5.08 | nM | ALA3399381 | nM | Rattus norvegicus | |||
16. | ALA3398482 | 27e | MED | = | 3 | mg kg-1 | ALA3399380 | mg kg-1 | Rattus norvegicus | |||
17. | ALA3398482 | 27e | Activity | 0 | ALA3399378 | Non-toxic | Rattus norvegicus | |||||
18. | ALA3398482 | 27e | Activity | 0 | ALA3399377 | Not Active | Rattus norvegicus | |||||
19. | ALA3398482 | 27e | Activity | 0 | ALA3399376 | Active | Rattus norvegicus | |||||
20. | ALA3398482 | 27e | Cmax | = | 728 | nM | ALA3399375 | nM | Rattus norvegicus |