# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3398482 | 27e | Activity | = | 66 | % | ALA3399383 | % | Homo sapiens | |||
2. | ALA3398482 | 27e | Kb | = | 6.06 | nM | ALA3399382 | nM | Rattus norvegicus | |||
3. | ALA3398482 | 27e | Kb | = | 5.08 | nM | ALA3399381 | nM | Rattus norvegicus | |||
4. | ALA3398482 | 27e | MED | = | 3 | mg kg-1 | ALA3399380 | mg kg-1 | Rattus norvegicus | |||
5. | ALA3398482 | 27e | Activity | 0 | ALA3399378 | Non-toxic | Rattus norvegicus | |||||
6. | ALA3398482 | 27e | Activity | 0 | ALA3399377 | Not Active | Rattus norvegicus | |||||
7. | ALA3398482 | 27e | Activity | 0 | ALA3399376 | Active | Rattus norvegicus | |||||
8. | ALA3398482 | 27e | Cmax | = | 728 | nM | ALA3399375 | nM | Rattus norvegicus | |||
9. | ALA3398482 | 27e | Activity | 0 | ALA3399374 | Dose-dependent effect | Rattus norvegicus | |||||
10. | ALA3398482 | 27e | solubility | = | 30.2 | ug ml-1 | ALA3399373 | ug.mL-1 | ||||
11. | ALA3398482 | 27e | Drugexcretion | = | 0.2 | % | ALA3399372 | % | ||||
12. | ALA3398482 | 27e | Drugexcretion | = | 0.4 | % | ALA3399370 | % | ||||
13. | ALA3398482 | 27e | Drug metabolism | = | 7.3 | % | ALA3399371 | % | Canis lupus familiaris | |||
14. | ALA3398482 | 27e | F | = | 80.2 | % | ALA3399369 | % | Canis lupus familiaris | |||
15. | ALA3398482 | 27e | Tmax | = | 0.667 | hr | ALA3399368 | hr | Canis lupus familiaris | |||
16. | ALA3398482 | 27e | t1/2 | = | 0.962 | hr | ALA3399367 | hr | Canis lupus familiaris | |||
17. | ALA3398482 | 27e | CL | = | 598 | ml/hr/kg | ALA3399366 | mL.min-1.kg-1 | Canis lupus familiaris | |||
18. | ALA3398482 | 27e | Vd | = | 745 | ml/kg | ALA3399365 | L.kg-1 | Canis lupus familiaris | |||
19. | ALA3398482 | 27e | Ratio | = | 0.06 | ALA3399364 | ||||||
20. | ALA3398482 | 27e | BPR | = | 0.17 | ALA3399363 |