# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3400467 | 16i, YM928 | IC50 | = | 2 | uM | ALA3406781 | 5.70 | nM | |||
2. | ALA3400467 | 16i, YM928 | ED50 | = | 7.4 | mg kg-1 | ALA3406783 | mg.kg-1 | Mus musculus | |||
3. | ALA3400467 | 16i, YM928 | AUC | = | 542 | ng.hr/ml | ALA3406784 | ng.hr.mL-1 | Rattus norvegicus | |||
4. | ALA3400467 | 16i, YM928 | AUC | = | 472.3 | ng.hr/ml | ALA3406785 | ng.hr.mL-1 | Rattus norvegicus | |||
5. | ALA3400467 | 16i, YM928 | CL | = | 1845.1 | ml/hr/kg | ALA3406786 | mL.min-1.kg-1 | Rattus norvegicus | |||
6. | ALA3400467 | 16i, YM928 | Vdss | = | 1176 | ml/kg | ALA3406787 | L.kg-1 | Rattus norvegicus | |||
7. | ALA3400467 | 16i, YM928 | t1/2 | = | 0.44 | hr | ALA3406788 | hr | Rattus norvegicus | |||
8. | ALA3400467 | 16i, YM928 | t1/2 | = | 0.58 | hr | ALA3406789 | hr | Rattus norvegicus | |||
9. | ALA3400467 | 16i, YM928 | Cmax | = | 425.1 | ng/ml | ALA3406790 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
10. | ALA3400467 | 16i, YM928 | Tmax | = | 0.25 | hr | ALA3406791 | hr | Rattus norvegicus | |||
11. | ALA3400467 | 16i, YM928 | F | = | 87.1 | % | ALA3406792 | % | Rattus norvegicus |