# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3401745 | 4a | INH | = | 56 | % | ALA3404109 | % | Homo sapiens | |||
2. | ALA3401745 | 4a | INH | = | 50 | % | ALA3404108 | % | Homo sapiens | |||
3. | ALA3401745 | 4a | Vd/F | = | 76.815 | L/Kg | ALA3404107 | L.kg-1 | Mus musculus | |||
4. | ALA3401745 | 4a | Vd/F | = | 1.65 | L/Kg | ALA3404106 | L.kg-1 | Mus musculus | |||
5. | ALA3401745 | 4a | CL/F | = | 1066.97 | ml/min.kg | ALA3404105 | mL.min-1.kg-1 | Mus musculus | |||
6. | ALA3401745 | 4a | CL/F | = | 204 | ml/min.kg | ALA3404104 | mL.min-1.kg-1 | Mus musculus | |||
7. | ALA3401745 | 4a | AUC | = | 156 | ng.hr/ml | ALA3404103 | ng.hr.mL-1 | Mus musculus | |||
8. | ALA3401745 | 4a | AUC | = | 71 | ng.hr/ml | ALA3404102 | ng.hr.mL-1 | Mus musculus | |||
9. | ALA3401745 | 4a | AUC | = | 81.8 | ng.hr/ml | ALA3404101 | ng.hr.mL-1 | Mus musculus | |||
10. | ALA3401745 | 4a | AUCt | = | 134 | ng.hr/ml | ALA3404100 | ng.hr.mL-1 | Mus musculus | |||
11. | ALA3401745 | 4a | AUCt | = | 69.4 | ng.hr/ml | ALA3404099 | ng.hr.mL-1 | Mus musculus | |||
12. | ALA3401745 | 4a | AUCt | = | 80 | ng.hr/ml | ALA3406027 | ng.hr.mL-1 | Mus musculus | |||
13. | ALA3401745 | 4a | C0 | = | 556 | ng/ml | ALA3406026 | ng/ml | Mus musculus | |||
14. | ALA3401745 | 4a | Tmax | = | 0.083 | hr | ALA3406025 | hr | Mus musculus | |||
15. | ALA3401745 | 4a | Tmax | = | 0.5 | hr | ALA3406024 | hr | Mus musculus | |||
16. | ALA3401745 | 4a | Cmax | = | 380 | ng/ml | ALA3406023 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
17. | ALA3401745 | 4a | Cmax | = | 105 | ng/ml | ALA3406022 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
18. | ALA3401745 | 4a | Cmax | = | 221 | ng/ml | ALA3406021 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
19. | ALA3401745 | 4a | t1/2 | = | 0.8 | hr | ALA3406020 | hr | Mus musculus | |||
20. | ALA3401745 | 4a | Drug metabolism | > | 95 | % | ALA3406019 | % | Mus musculus |