| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3403619 | 22b, enantiomer-2 | Activity | 0 | ALA3404980 | Not Active | ||||||
| 2. | ALA3403619 | 22b, enantiomer-2 | IC50 | = | 13 | ng/ml | ALA3404979 | ug.mL-1 | Rattus norvegicus | |||
| 3. | ALA3403619 | 22b, enantiomer-2 | F | < | 2 | % | ALA3404978 | % | Rattus norvegicus | |||
| 4. | ALA3403619 | 22b, enantiomer-2 | t1/2 | = | 9.49 | hr | ALA3404977 | hr | Rattus norvegicus | |||
| 5. | ALA3403619 | 22b, enantiomer-2 | AUClast | = | 1.32 | hr.microg/ml | ALA3404976 | ng.hr.mL-1 | Rattus norvegicus | |||
| 6. | ALA3403619 | 22b, enantiomer-2 | Cmax | = | 1.96 | g/ml | ALA3404975 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 7. | ALA3403619 | 22b, enantiomer-2 | Vdss | = | 6.71 | L/Kg | ALA3404974 | L.kg-1 | Rattus norvegicus | |||
| 8. | ALA3403619 | 22b, enantiomer-2 | CL | = | 0.643 | L/hr/kg | ALA3404973 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 9. | ALA3403619 | 22b, enantiomer-2 | t1/2 | > | 60 | min | ALA3404972 | hr | Homo sapiens | |||
| 10. | ALA3403619 | 22b, enantiomer-2 | t1/2 | > | 60 | min | ALA3404966 | hr | Rattus norvegicus | |||
| 11. | ALA3403619 | 22b, enantiomer-2 | t1/2 | > | 60 | min | ALA3404965 | hr | Mus musculus | |||
| 12. | ALA3403619 | 22b, enantiomer-2 | Emax | = | 82 | % | ALA3404971 | % | Homo sapiens | |||
| 13. | ALA3403619 | 22b, enantiomer-2 | EC50 | = | 5.8 | nM | ALA3404970 | 8.24 | nM | Homo sapiens | ||
| 14. | ALA3403619 | 22b, enantiomer-2 | Emax | = | 77 | % | ALA3404969 | % | Homo sapiens | |||
| 15. | ALA3403619 | 22b, enantiomer-2 | EC50 | = | 26 | nM | ALA3404968 | 7.58 | nM | Homo sapiens | ||
| 16. | ALA3403619 | 22b, enantiomer-2 | EC50 | = | 10000 | nM | ALA3404967 | 5.00 | nM | Homo sapiens | ||
| 17. | ALA3403619 | 22b, enantiomer-2 | EC50 | = | 10000 | nM | ALA3404964 | 5.00 | nM | Homo sapiens | ||
| 18. | ALA3403619 | 22b, enantiomer-2 | Emax | = | 104 | % | ALA3404963 | % | Homo sapiens | |||
| 19. | ALA3403619 | 22b, enantiomer-2 | EC50 | = | 1.2 | nM | ALA3404962 | 8.92 | nM | Homo sapiens | ||
| 20. | ALA3403619 | 22b, enantiomer-2 | Emax | = | 82 | % | ALA3404961 | % | Macaca mulatta |
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