# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3408073 | 75b | ED50 | = | 3.1 | mg kg-1 | ALA3412603 | mg.kg-1 | Staphylococcus aureus | |||
2. | ALA3408073 | 75b | ED50 | = | 1.7 | mg kg-1 | ALA3412602 | mg.kg-1 | Staphylococcus aureus | |||
3. | ALA3408073 | 75b | ED50 | = | 7.6 | mg kg-1 | ALA3412601 | mg.kg-1 | Staphylococcus aureus | |||
4. | ALA3408073 | 75b | F | = | 97 | % | ALA3412600 | % | Mus musculus | |||
5. | ALA3408073 | 75b | beta t1/2 | = | 18.6 | hr | ALA3412599 | hr | Mus musculus | |||
6. | ALA3408073 | 75b | alphat1/2 | = | 15.9 | hr | ALA3412598 | hr | Mus musculus | |||
7. | ALA3408073 | 75b | t1/2abs | = | 0.83 | hr | ALA3412597 | hr | Mus musculus | |||
8. | ALA3408073 | 75b | beta t1/2 | = | 9.6 | hr | ALA3412596 | hr | Mus musculus | |||
9. | ALA3408073 | 75b | alphat1/2 | = | 0.54 | min | ALA3412595 | hr | Mus musculus | |||
10. | ALA3408073 | 75b | Vd | = | 4.73 | L/Kg | ALA3412594 | L.kg-1 | Mus musculus | |||
11. | ALA3408073 | 75b | Tmax | = | 6 | hr | ALA3412593 | hr | Mus musculus | |||
12. | ALA3408073 | 75b | Cmax | = | 2.34 | ug ml-1 | ALA3412592 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
13. | ALA3408073 | 75b | AUC | = | 4060 | microg.min/mL | ALA3412591 | ng.hr.mL-1 | Mus musculus | |||
14. | ALA3408073 | 75b | AUC | = | 3520 | microg.min/mL | ALA3412590 | ng.hr.mL-1 | Mus musculus | |||
15. | ALA3408073 | 75b | AUC | = | 3060 | microg.min/mL | ALA3412589 | ng.hr.mL-1 | Mus musculus | |||
16. | ALA3408073 | 75b | AUC | = | 3140 | microg.min/mL | ALA3412588 | ng.hr.mL-1 | Mus musculus | |||
17. | ALA3408073 | 75b | Ratio | = | 2 | ALA3412587 | Enterococcus faecium | |||||
18. | ALA3408073 | 75b | Ratio | = | 2 | ALA3412586 | Staphylococcus aureus | |||||
19. | ALA3408073 | 75b | MBC | = | 2 | ug ml-1 | ALA3412585 | ug ml-1 | Staphylococcus aureus | |||
20. | ALA3408073 | 75b | Activity | 0 | ALA3412583 | Active | Staphylococcus aureus |