# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3415446 | 11 | Cmax | = | 34 | ug ml-1 | ALA3420794 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
2. | ALA3415446 | 11 | t1/2 | = | 0.7 | hr | ALA3420793 | hr | Mus musculus | |||
3. | ALA3415446 | 11 | F | <= | 1 | % | ALA3420783 | % | Mus musculus | |||
4. | ALA3415446 | 11 | AUC | = | 125 | ug/L/h | ALA3420562 | ng.hr.mL-1 | Mus musculus | |||
5. | ALA3415446 | 11 | AUC | = | 3850 | ug/L/h | ALA3420560 | ng.hr.mL-1 | Mus musculus | |||
6. | ALA3415446 | 11 | CL | = | 108 | ml/min.kg | ALA3420558 | mL.min-1.kg-1 | Mus musculus | |||
7. | ALA3415446 | 11 | INH | 0 | ALA3420557 | Dose-dependent effect | % | Homo sapiens | ||||
8. | ALA3415446 | 11 | INH | 0 | ALA3420554 | Not Active | % | Homo sapiens | ||||
9. | ALA3415446 | 11 | CLH | = | 26 | ml/min.kg | ALA3420553 | mL.min-1.kg-1 | Mus musculus | |||
10. | ALA3415446 | 11 | CLH | = | 4.6 | ml/min.kg | ALA3420552 | mL.min-1.kg-1 | Homo sapiens | |||
11. | ALA3415446 | 11 | solubility | = | 33 | ug ml-1 | ALA3420551 | ug.mL-1 | ||||
12. | ALA3415446 | 11 | IC50 | = | 0.21 | uM | ALA3420550 | 6.68 | nM | Homo sapiens | ||
13. | ALA3415446 | 11 | IC50 | = | 0.38 | uM | ALA3420277 | 6.42 | nM | Homo sapiens | ||
14. | ALA3415446 | 11 | IC50 | = | 19.5 | uM | ALA3420276 | 4.71 | nM | Homo sapiens | ||
15. | ALA3415446 | 11 | EC50 | = | 5.9 | uM | ALA3420275 | 5.23 | nM | Homo sapiens |