Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	Syk-IN-1	11	Ratio	=	100		ALA3626612
2.	Syk-IN-1	11	Ratio	=	100		ALA3626611
3.	Syk-IN-1	11	Drug uptake	=	3866	ng/g	ALA3626610			ng/g	Rattus norvegicus
4.	Syk-IN-1	11	Drug uptake	=	9175	ng/g	ALA3626609			ng/g	Rattus norvegicus
5.	Syk-IN-1	11	Drug uptake	=	41	ng/g	ALA3626608			ng/g	Rattus norvegicus
6.	Syk-IN-1	11	INH		0		ALA3626607		Not Active	%	Homo sapiens
7.	Syk-IN-1	11	IC50	=	28	uM	ALA3626606	4.55		nM	Homo sapiens
8.	Syk-IN-1	11	Cmax/dose	=	80	nM	ALA3627499			nM	Rattus norvegicus
9.	Syk-IN-1	11	F	=	60	%	ALA3627498			%	Rattus norvegicus
10.	Syk-IN-1	11	AUC/dose	=	1449	nM.hr	ALA3627497			nM.hr	Rattus norvegicus
11.	Syk-IN-1	11	IC50	=	35	nM	ALA3627444	7.46		nM	Homo sapiens
12.	Syk-IN-1	11	IC50	=	367	nM	ALA3627446	6.43		nM	Homo sapiens
13.	Syk-IN-1	11	CL	=	31	ml/min.Kg	ALA3627447			mL.min-1.kg-1	Rattus norvegicus
14.	Syk-IN-1	11	Vdss	=	16.4	L/Kg	ALA3627448			L.kg-1	Rattus norvegicus
15.	Syk-IN-1	11	MRT	=	8.7	hr	ALA3627449			hr	Rattus norvegicus
16.	Syk-IN-1	11	IC50	=	99	nM	ALA3627445	7.00		nM	Homo sapiens
17.	Syk-IN-1	11	Stability	=	35.7	%	ALA3419938			%
18.	Syk-IN-1	11	Stability	=	57	%	ALA3419937			%
19.	Syk-IN-1	11	Stability	=	58.2	%	ALA3419936			%
20.	Syk-IN-1	11	Stability	=	78.5	%	ALA3419935			%