| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3417585 | 1R,6S-25 | EC50 | = | 0.7 | nM | ALA3421336 | 9.15 | nM | Homo sapiens | ||
| 2. | ALA3417585 | 1R,6S-25 | Activity | 0 | ALA3421331 | Non-toxic | Rattus norvegicus | |||||
| 3. | ALA3417585 | 1R,6S-25 | Activity | 0 | ALA3421330 | Non-toxic | Rattus norvegicus | |||||
| 4. | ALA3417585 | 1R,6S-25 | FC | = | 2.8 | ALA3421329 | Rattus norvegicus | |||||
| 5. | ALA3417585 | 1R,6S-25 | Activity | 0 | ALA3421328 | Not Active | Rattus norvegicus | |||||
| 6. | ALA3417585 | 1R,6S-25 | Time | = | 197 | min | ALA3421327 | hr | Rattus norvegicus | |||
| 7. | ALA3417585 | 1R,6S-25 | AUC | = | 233 | min | ALA3421326 | min | Rattus norvegicus | |||
| 8. | ALA3417585 | 1R,6S-25 | AUC | = | 158 | min | ALA3421325 | min | Rattus norvegicus | |||
| 9. | ALA3417585 | 1R,6S-25 | AUC | = | 128 | min | ALA3421324 | min | Rattus norvegicus | |||
| 10. | ALA3417585 | 1R,6S-25 | Activity | 0 | ALA3421323 | Dose-dependent effect | Rattus norvegicus | |||||
| 11. | ALA3417585 | 1R,6S-25 | Activity | 0 | ALA3421322 | Dose-dependent effect | Rattus norvegicus | |||||
| 12. | ALA3417585 | 1R,6S-25 | ED50 | = | 0.14 | mg kg-1 | ALA3421322 | mg.kg-1 | Rattus norvegicus | |||
| 13. | ALA3417585 | 1R,6S-25 | F | = | 136 | % | ALA3421321 | % | Macaca mulatta | |||
| 14. | ALA3417585 | 1R,6S-25 | Cmax | = | 764 | ng/ml | ALA3421096 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Macaca mulatta | ||
| 15. | ALA3417585 | 1R,6S-25 | AUCt | = | 9574 | ng.hr/ml | ALA3421095 | ng.hr.mL-1 | Macaca mulatta | |||
| 16. | ALA3417585 | 1R,6S-25 | CL | = | 6 | ml/min.kg | ALA3421094 | mL.min-1.kg-1 | Macaca mulatta | |||
| 17. | ALA3417585 | 1R,6S-25 | Vdss | = | 4 | L/Kg | ALA3421093 | L.kg-1 | Macaca mulatta | |||
| 18. | ALA3417585 | 1R,6S-25 | t1/2 | = | 7.7 | hr | ALA3421092 | hr | Macaca mulatta | |||
| 19. | ALA3417585 | 1R,6S-25 | BPR | = | 2.1 | ALA3421091 | Canis lupus familiaris | |||||
| 20. | ALA3417585 | 1R,6S-25 | F | = | 115 | % | ALA3421090 | % | Canis lupus familiaris |
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