| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3421730 | 3 | K(p,uu,brain) | = | 1 | ALA4372479 | ||||||
| 2. | ALA3421730 | 3 | EC50 | = | 5.8 | nM | ALA4372466 | 8.24 | nM | Homo sapiens | ||
| 3. | ALA3421730 | 3 | Emax | = | 75.6 | % | ALA4372460 | % | Homo sapiens | |||
| 4. | ALA3421730 | 3 | EC50 | = | 8.6 | nM | ALA4372465 | 8.07 | nM | |||
| 5. | ALA3421730 | 3 | Emax | = | 85.2 | % | ALA4372464 | % | ||||
| 6. | ALA3421730 | 3 | EC50 | = | 12 | nM | ALA4372463 | 7.92 | nM | |||
| 7. | ALA3421730 | 3 | Emax | = | 80 | % | ALA4372462 | % | ||||
| 8. | ALA3421730 | 3 | EC50 | = | 162 | nM | ALA4372461 | 6.79 | nM | Rattus norvegicus | ||
| 9. | ALA3421730 | 3 | Emax | = | 39.9 | % | ALA4372483 | % | Rattus norvegicus | |||
| 10. | ALA3421730 | 3 | EC50 | = | 312 | nM | ALA4372484 | 6.51 | nM | Mus musculus | ||
| 11. | ALA3421730 | 3 | FC | <= | 21 | ALA4372459 | Homo sapiens | |||||
| 12. | ALA3421730 | 3 | Emax | = | 50 | % | ALA4372459 | % | Homo sapiens | |||
| 13. | ALA3421730 | 3 | F | = | 9 | % | ALA4337872 | % | ||||
| 14. | ALA3421730 | 3 | Tmax | = | 0.5 | hr | ALA4337871 | hr | ||||
| 15. | ALA3421730 | 3 | Cmax | = | 219 | nM | ALA4337870 | nM | ||||
| 16. | ALA3421730 | 3 | AUC | = | 367 | nM.hr | ALA4337869 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 17. | ALA3421730 | 3 | Vdss | = | 1.65 | L/Kg | ALA4337868 | L.kg-1 | ||||
| 18. | ALA3421730 | 3 | AUC | = | 406 | nM.hr | ALA4337866 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 19. | ALA3421730 | 3 | t1/2 | = | 0.23 | hr | ALA4337865 | hr | ||||
| 20. | ALA3421730 | 3 | CL | = | 96.9 | ml/min.kg | ALA4337864 | mL.min-1.kg-1 |
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