# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3422010 | 31 | Ki | = | 76 | nM | ALA3425008 | 7.12 | nM | Rattus norvegicus | ||
2. | ALA3422010 | 31 | Fu | = | 0.043 | ALA3425263 | Macaca mulatta | |||||
3. | ALA3422010 | 31 | INH | 0 | ALA3425262 | Not Active | % | Macaca fascicularis | ||||
4. | ALA3422010 | 31 | INH | 0 | ALA3425261 | Active | % | Macaca fascicularis | ||||
5. | ALA3422010 | 31 | INH | = | 40 | % | ALA3425175 | % | Macaca fascicularis | |||
6. | ALA3422010 | 31 | Tmax | = | 60 | min | ALA3425187 | hr | Macaca fascicularis | |||
7. | ALA3422010 | 31 | fAUC | = | 526 | nM.hr | ALA3425190 | uM.hr | Macaca fascicularis | |||
8. | ALA3422010 | 31 | fAUC | = | 64.6 | nM.hr | ALA3425193 | uM.hr | Macaca fascicularis | |||
9. | ALA3422010 | 31 | F | = | 25 | % | ALA3425196 | % | Macaca fascicularis | |||
10. | ALA3422010 | 31 | F | = | 12 | % | ALA3425199 | % | Macaca fascicularis | |||
11. | ALA3422010 | 31 | Ratio | = | 9.4 | ALA3425204 | ||||||
12. | ALA3422010 | 31 | Ratio | = | 1 | ALA3425248 | ||||||
13. | ALA3422010 | 31 | fAUC | = | 1055 | nM.hr | ALA3425251 | uM.hr | Macaca fascicularis | |||
14. | ALA3422010 | 31 | Tmax | = | 90 | min | ALA3425254 | hr | Macaca fascicularis | |||
15. | ALA3422010 | 31 | t1/2 | = | 210 | min | ALA3425178 | hr | Macaca fascicularis | |||
16. | ALA3422010 | 31 | Vdss | = | 1.52 | L/Kg | ALA3425177 | L.kg-1 | Macaca fascicularis | |||
17. | ALA3422010 | 31 | CL | = | 16.5 | ml/min.kg | ALA3425182 | mL.min-1.kg-1 | Macaca fascicularis | |||
18. | ALA3422010 | 31 | fCmax | = | 237 | nM | ALA3425181 | nM | Macaca fascicularis | |||
19. | ALA3422010 | 31 | fCmax | = | 17.9 | nM | ALA3425180 | nM | Macaca fascicularis | |||
20. | ALA3422010 | 31 | Ratio | = | 1.5 | ALA3425189 |