# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3422874 | 9b | BPR | = | 0.13 | ALA3424086 | ||||||
2. | ALA3422874 | 9b | Drug uptake | = | 0.156 | ug ml-1 | ALA3424085 | ug ml-1 | Rattus norvegicus | |||
3. | ALA3422874 | 9b | Cp | = | 0.07 | ug ml-1 | ALA3424084 | ug ml-1 | Rattus norvegicus | |||
4. | ALA3422874 | 9b | Cp | = | 1.19 | ug ml-1 | ALA3424083 | ug ml-1 | Rattus norvegicus | |||
5. | ALA3422874 | 9b | Drugexcretion | = | 0 | % | ALA3424082 | % | Rattus norvegicus | |||
6. | ALA3422874 | 9b | Tmax | = | 72 | min | ALA3424081 | hr | Rattus norvegicus | |||
7. | ALA3422874 | 9b | Cmax | = | 1.41 | ug ml-1 | ALA3424080 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
8. | ALA3422874 | 9b | beta t1/2 | = | 88.96 | min | ALA3424079 | hr | Rattus norvegicus | |||
9. | ALA3422874 | 9b | AUClast | = | 245.52 | microg.min/mL | ALA3424078 | ng.hr.mL-1 | Rattus norvegicus | |||
10. | ALA3422874 | 9b | AUC | = | 254.96 | microg.min/mL | ALA3424077 | ng.hr.mL-1 | Rattus norvegicus | |||
11. | ALA3422874 | 9b | F | = | 45.8 | % | ALA3424076 | % | Rattus norvegicus | |||
12. | ALA3422874 | 9b | BPR | = | 0.14 | ALA3424075 | ||||||
13. | ALA3422874 | 9b | Drug uptake | = | 0.138 | ug ml-1 | ALA3424074 | ug ml-1 | Rattus norvegicus | |||
14. | ALA3422874 | 9b | Cp | = | 0.08 | ug ml-1 | ALA3424073 | ug ml-1 | Rattus norvegicus | |||
15. | ALA3422874 | 9b | Cp | = | 1.24 | ug ml-1 | ALA3424072 | ug ml-1 | Rattus norvegicus | |||
16. | ALA3422874 | 9b | Drugexcretion | = | 0 | % | ALA3424071 | % | Rattus norvegicus | |||
17. | ALA3422874 | 9b | Vdss(app) | = | 1656.19 | ml/kg | ALA3424068 | L.kg-1 | Rattus norvegicus | |||
18. | ALA3422874 | 9b | MRT | = | 78.49 | min | ALA3424069 | hr | Rattus norvegicus | |||
19. | ALA3422874 | 9b | CL | = | 20.15 | ml/min.kg | ALA3424070 | mL.min-1.kg-1 | Rattus norvegicus | |||
20. | ALA3422874 | 9b | beta t1/2 | = | 109.91 | min | ALA3424067 | hr | Rattus norvegicus |