# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3426225 | 1j | Vdss(app) | = | 38.57 | L/Kg | ALA3428275 | L.kg-1 | Rattus norvegicus | |||
2. | ALA3426225 | 1j | CL | = | 2.1 | L/hr/kg | ALA3428274 | mL.min-1.kg-1 | Rattus norvegicus | |||
3. | ALA3426225 | 1j | Tmax | = | 12 | hr | ALA3428273 | hr | Rattus norvegicus | |||
4. | ALA3426225 | 1j | Cmax | = | 214.63 | ug/L | ALA3428272 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
5. | ALA3426225 | 1j | beta t1/2 | = | 12.76 | hr | ALA3428271 | hr | Rattus norvegicus | |||
6. | ALA3426225 | 1j | AUC | = | 4772.5 | ug/L/h | ALA3428270 | ng.hr.mL-1 | Rattus norvegicus | |||
7. | ALA3426225 | 1j | Activity | 0 | ALA3428269 | Active | Homo sapiens | |||||
8. | ALA3426225 | 1j | Activity | 0 | ALA3428268 | Active | Homo sapiens | |||||
9. | ALA3426225 | 1j | INH | 0 | ALA3428267 | Active | % | Mus musculus | ||||
10. | ALA3426225 | 1j | INH | 0 | ALA3428266 | Active | % | Mus musculus | ||||
11. | ALA3426225 | 1j | INH | 0 | ALA3428265 | Active | % | Mus musculus | ||||
12. | ALA3426225 | 1j | Activity | 0 | ALA3428262 | Non-toxic | Mus musculus | |||||
13. | ALA3426225 | 1j | TGI | 0 | ALA3428261 | Active | Homo sapiens | |||||
14. | ALA3426225 | 1j | TGI | > | 100 | % | ALA3428260 | % | Homo sapiens | |||
15. | ALA3426225 | 1j | INH | 0 | ALA3428259 | Active | % | Homo sapiens | ||||
16. | ALA3426225 | 1j | Activity | 0 | ALA3428257 | Not Active | ||||||
17. | ALA3426225 | 1j | INH | 0 | ALA3428256 | Active | % | |||||
18. | ALA3426225 | 1j | INH | 0 | ALA3428255 | Active | % | |||||
19. | ALA3426225 | 1j | INH | 0 | ALA3428254 | Active | % | Homo sapiens | ||||
20. | ALA3426225 | 1j | IC50 | = | 0.03 | uM | ALA3428253 | 7.52 | nM | Homo sapiens |