# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3426305 | 20, GNE-7056 | logD | = | 3.6 | ALA3428429 | ||||||
2. | ALA3426305 | 20, GNE-7056 | Ratio IC50 | = | 1070 | ALA3428428 | ||||||
3. | ALA3426305 | 20, GNE-7056 | Cp | = | 80 | uM | ALA3429288 | uM | Mus musculus | |||
4. | ALA3426305 | 20, GNE-7056 | Activity | = | 100 | % | ALA3429287 | % | Mus musculus | |||
5. | ALA3426305 | 20, GNE-7056 | Activity | = | 95 | % | ALA3429286 | % | Mus musculus | |||
6. | ALA3426305 | 20, GNE-7056 | Activity | = | 62 | % | ALA3429285 | % | Mus musculus | |||
7. | ALA3426305 | 20, GNE-7056 | %max | = | 98 | % | ALA3429139 | % | Mus musculus | |||
8. | ALA3426305 | 20, GNE-7056 | Activity | = | 90 | % | ALA3429138 | % | Mus musculus | |||
9. | ALA3426305 | 20, GNE-7056 | Activity | = | 55 | % | ALA3429137 | % | Mus musculus | |||
10. | ALA3426305 | 20, GNE-7056 | Activity | 0 | ALA3428435 | Dose-dependent effect | Mus musculus | |||||
11. | ALA3426305 | 20, GNE-7056 | IC50 | = | 83 | uM | ALA3428434 | 4.08 | nM | |||
12. | ALA3426305 | 20, GNE-7056 | INH | = | 3.6 | % | ALA3428433 | % | Homo sapiens | |||
13. | ALA3426305 | 20, GNE-7056 | CLH | = | 13 | ml/min.kg | ALA3428432 | mL.min-1.kg-1 | Homo sapiens | |||
14. | ALA3426305 | 20, GNE-7056 | PPB | = | 94 | % | ALA3428431 | % | ||||
15. | ALA3426305 | 20, GNE-7056 | permeability | = | 1.9 | ucm/s | ALA3428430 | ucm/s | Canis lupus familiaris | |||
16. | ALA3426305 | 20, GNE-7056 | Kinetic_solubility | = | 43 | uM | ALA3428427 | nM | ||||
17. | ALA3426305 | 20, GNE-7056 | Kinetic_solubility | = | 45 | uM | ALA3428427 | nM | ||||
18. | ALA3426305 | 20, GNE-7056 | Ratio Ki | = | 2200 | ALA3428426 | ||||||
19. | ALA3426305 | 20, GNE-7056 | Ratio Ki | = | 8000 | ALA3428426 | ||||||
20. | ALA3426305 | 20, GNE-7056 | Ki | = | 0.66 | uM | ALA3428283 | 6.18 | nM | Homo sapiens |