# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3426543 | 1a | EC50 | = | 0.012 | uM | ALA3429681 | 7.92 | nM | dengue virus type 2 | ||
2. | ALA3426543 | 1a | EC50 | = | 0.012 | uM | ALA3429682 | 7.92 | nM | dengue virus type 2 | ||
3. | ALA3426543 | 1a | CC50 | > | 10 | uM | ALA3429683 | nM | Homo sapiens | |||
4. | ALA3426543 | 1a | solubility | = | 11 | uM | ALA3429684 | nM | ||||
5. | ALA3426543 | 1a | logP | = | 4.9 | ALA3429685 | ||||||
6. | ALA3426543 | 1a | ERH | = | 66 | % | ALA3429686 | % | ||||
7. | ALA3426543 | 1a | t1/2 | = | 31 | min | ALA3429687 | hr | Mus musculus | |||
8. | ALA3426543 | 1a | Cmax | = | 0.78 | ug ml-1 | ALA3429688 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
9. | ALA3426543 | 1a | Tmax | = | 2 | hr | ALA3429689 | hr | Rattus norvegicus | |||
10. | ALA3426543 | 1a | AUC | = | 9.5 | hr.microg/ml | ALA3429690 | ng.hr.mL-1 | Rattus norvegicus | |||
11. | ALA3426543 | 1a | F | = | 33 | % | ALA3429691 | % | Rattus norvegicus | |||
12. | ALA3426543 | 1a | Vdss | = | 4.3 | L/Kg | ALA3429692 | L.kg-1 | Rattus norvegicus | |||
13. | ALA3426543 | 1a | CL | = | 15.1 | ml/min.kg | ALA3429693 | mL.min-1.kg-1 | Rattus norvegicus | |||
14. | ALA3426543 | 1a | beta t1/2 | = | 3.8 | hr | ALA3429694 | hr | Rattus norvegicus | |||
15. | ALA3426543 | 1a | EC50 | > | 5 | nM | ALA4431571 | nM | Hepacivirus hominis | |||
16. | ALA3426543 | 1a | EC50 | > | 20 | nM | ALA4431570 | nM | dengue virus type 4 | |||
17. | ALA3426543 | 1a | EC50 | = | 10 | nM | ALA4431569 | 8.00 | nM | dengue virus type 3 | ||
18. | ALA3426543 | 1a | EC50 | = | 10 | nM | ALA4431568 | 8.00 | nM | dengue virus type 2 | ||
19. | ALA3426543 | 1a | EC50 | > | 20 | uM | ALA4431567 | nM | dengue virus type 1 | |||
20. | ALA3426543 | 1a | EC50 | = | 1.9 | uM | ALA4431566 | 5.72 | nM | dengue virus type 2 |