# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA113841 | 9, Zankiren, A-72517 | IC50 | = | 1.1 | nM | ALA975287 | 8.96 | nM | Homo sapiens | ||
2. | ALA113841 | 9, Zankiren, A-72517 | IC50 | = | 1400 | nM | ALA805018 | 5.85 | nM | Rattus norvegicus | ||
3. | ALA113841 | 9, Zankiren, A-72517 | IC50 | = | 110 | nM | ALA795933 | 6.96 | nM | Homo sapiens | ||
4. | ALA113841 | 9, Zankiren, A-72517 | IC50 | = | 0.24 | nM | ALA801750 | 9.62 | nM | Homo sapiens | ||
5. | ALA113841 | 9, Zankiren, A-72517 | F | = | 23 | % | ALA625396 | % | ||||
6. | ALA113841 | 9, Zankiren, A-72517 | Activity | = | 470 | ng ml-1 | ALA628482 | ng ml-1 | Rattus norvegicus | |||
7. | ALA113841 | 9, Zankiren, A-72517 | AUC | = | 620 | ng hr ml-1 | ALA624555 | ng.hr.mL-1 | Rattus norvegicus | |||
8. | ALA113841 | 9, Zankiren, A-72517 | F | = | 82 | % | ALA625438 | % | ||||
9. | ALA113841 | 9, Zankiren, A-72517 | Activity | = | 940 | ng ml-1 | ALA628478 | ng ml-1 | Mustela putorius furo | |||
10. | ALA113841 | 9, Zankiren, A-72517 | AUC | = | 1500 | ng hr ml-1 | ALA624551 | ng.hr.mL-1 | Mustela putorius furo | |||
11. | ALA113841 | 9, Zankiren, A-72517 | Bioavailabiility | = | 5.1 | % | ALA625441 | % | ||||
12. | ALA113841 | 9, Zankiren, A-72517 | Activity | = | 130 | ng ml-1 | ALA628480 | ng ml-1 | ||||
13. | ALA113841 | 9, Zankiren, A-72517 | AUC | = | 340 | ng hr ml-1 | ALA624553 | ng.hr.mL-1 | ||||
14. | ALA113841 | 9, Zankiren, A-72517 | Activity | = | 2400 | ng ml-1 | ALA628477 | ng ml-1 | ||||
15. | ALA113841 | 9, Zankiren, A-72517 | AUC | = | 3800 | ng hr ml-1 | ALA623852 | ng.hr.mL-1 | ||||
16. | ALA113841 | 9, Zankiren, A-72517 | Change | = | 37 | % | ALA626615 | % | ||||
17. | ALA113841 | 9, Zankiren, A-72517 | Solubility | = | 0.001 | mg ml-1 | ALA632909 | ug.mL-1 | ||||
18. | ALA113841 | 9, Zankiren, A-72517 | logD | = | 4.57 | ALA640879 | ||||||
19. | ALA113841 | 9, Zankiren, A-72517 | IC50 | = | 0.2 | nM | ALA801711 | 9.70 | nM | Homo sapiens | ||
20. | ALA113841 | 9, Zankiren, A-72517 | IC50 | = | 1.1 | nM | ALA801711 | 8.96 | nM | Homo sapiens |