# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA17125 | 8 | pIC50 | < | 4.7 | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | |||
2. | ALA17125 | 8 | IC50 | > | 0 | M | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
3. | ALA17125 | 8 | CL | = | 28 | mL/min/kg | ALA1614675 | mL.min-1.kg-1 | ||||
4. | ALA17125 | 8 | DNAUC | = | 20 | kg.min/L | ALA1614691 | kg.min/L | ||||
5. | ALA17125 | 8 | CL | = | 13 | mL/min/kg | ALA1614679 | mL.min-1.kg-1 | ||||
6. | ALA17125 | 8 | CL | = | 11 | mL/min/kg | ALA1614677 | mL.min-1.kg-1 | ||||
7. | ALA17125 | 8 | CL | = | 4 | mL/min/kg | ALA1614681 | mL.min-1.kg-1 | ||||
8. | ALA17125 | 8 | Vdss | = | 3.3 | mL/min/kg | ALA1614676 | mL/min/kg | ||||
9. | ALA17125 | 8 | Vdss | = | 1.2 | L/kg | ALA1614678 | L.kg-1 | ||||
10. | ALA17125 | 8 | Vdss | = | 0.85 | L/kg | ALA1614680 | L.kg-1 | ||||
11. | ALA17125 | 8 | Vdss | = | 0.35 | L/kg | ALA1614682 | L.kg-1 | ||||
12. | ALA17125 | 8 | DNAUC | = | 152.38 | kg.min/L | ALA1614694 | kg.min/L | ||||
13. | ALA17125 | 8 | DNAUC | = | 84 | kg.min/L | ALA1614692 | kg.min/L | ||||
14. | ALA17125 | 8 | DNAUC | = | 39.2 | kg.min/L | ALA1614693 | kg.min/L | ||||
15. | ALA17125 | 8 | Vdss | = | 0.39 | L/Kg | ALA1028549 | L.kg-1 | Homo sapiens | |||
16. | ALA17125 | 8 | Inotropic effect | = | 66 | ALA651256 | Homo sapiens | |||||
17. | ALA17125 | 8 | PDE inhibition | 65 | ALA824379 | Not Determined | Homo sapiens | |||||
18. | ALA17125 | 8 | PDE inhibition | = | 64 | ALA824379 | Homo sapiens | |||||
19. | ALA17125 | 8 | IC50 | = | 4 | uM | ALA767973 | 5.40 | nM | |||
20. | ALA17125 | 8 | C20 | = | 0.2 | uM | ALA678622 | uM | Mustela putorius furo |