# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3526472 | [14C]-Brivanib alaninate | AUC | = | 65627.4 | ugequiv/l.hr | ALA3538200 | ugequiv/l.hr | Homo sapiens | |||
2. | ALA3526472 | [14C]-Brivanib alaninate | Drug metabolism | 0 | ALA3539750 | metabolite_detected | Homo sapiens | |||||
3. | ALA3526472 | [14C]-Brivanib alaninate | Drug metabolism | 0 | ALA3532430 | metabolite_detected | Homo sapiens | |||||
4. | ALA3526472 | [14C]-Brivanib alaninate | Drug metabolism | 0 | ALA3532429 | metabolite_detected | Homo sapiens | |||||
5. | ALA3526472 | [14C]-Brivanib alaninate | Drug metabolism | 0 | ALA3532428 | metabolite_detected | Homo sapiens | |||||
6. | ALA3526472 | [14C]-Brivanib alaninate | Drug metabolism | 0 | ALA3532427 | metabolite_not_detected | Homo sapiens | |||||
7. | ALA3526472 | [14C]-Brivanib alaninate | Drug metabolism | 0 | ALA3532426 | metabolite_not_detected | Homo sapiens | |||||
8. | ALA3526472 | [14C]-Brivanib alaninate | Drug metabolism | 0 | ALA3535255 | metabolite_not_detected | Homo sapiens | |||||
9. | ALA3526472 | [14C]-Brivanib alaninate | Drug metabolism | 0 | ALA3535252 | metabolite_detected | Homo sapiens | |||||
10. | ALA3526472 | [14C]-Brivanib alaninate | Drug metabolism | 0 | ALA3535251 | metabolite_detected | Homo sapiens | |||||
11. | ALA3526472 | [14C]-Brivanib alaninate | AUC | = | 139766 | ugequiv/l.hr | ALA3538198 | ugequiv/l.hr | Rattus norvegicus | |||
12. | ALA3526472 | [14C]-Brivanib alaninate | AUCt | = | 203.8 | microg.hr/mL | ALA3540343 | ng.hr.mL-1 | Homo sapiens | |||
13. | ALA3526472 | [14C]-Brivanib alaninate | Radiolabel recovery | = | 93.72 | % | ALA3540424 | % | Homo sapiens | |||
14. | ALA3526472 | [14C]-Brivanib alaninate | Radiolabel recovery | = | 93.68 | % | ALA3540125 | % | Rattus norvegicus | |||
15. | ALA3526472 | [14C]-Brivanib alaninate | Radiolabel recovery | = | 89.79 | % | ALA3540132 | % | Macaca fascicularis | |||
16. | ALA3526472 | [14C]-Brivanib alaninate | Radiolabel recovery | = | 88.99 | % | ALA3540129 | % | Rattus norvegicus | |||
17. | ALA3526472 | [14C]-Brivanib alaninate | Radiolabel recovery | = | 83.58 | % | ALA3540124 | % | ||||
18. | ALA3526472 | [14C]-Brivanib alaninate | Radiolabel recovery | = | 81.43 | % | ALA3540421 | % | Macaca fascicularis | |||
19. | ALA3526472 | [14C]-Brivanib alaninate | Radiolabel recovery | = | 78.35 | % | ALA3540127 | % | ||||
20. | ALA3526472 | [14C]-Brivanib alaninate | Radiolabel recovery | = | 47.66 | % | ALA3540419 | % |