# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3526580 | E2074 | AUC | = | 1.55 | microg.hr/mL | ALA3529945 | ng.hr.mL-1 | Macaca fascicularis | |||
2. | ALA3526580 | E2074 | CLH | = | 1.83 | L/hr/kg | ALA3529042 | mL.min-1.kg-1 | Canis lupus familiaris | |||
3. | ALA3526580 | E2074 | t1/2 | = | 1.96 | hr | ALA3529937 | hr | Macaca fascicularis | |||
4. | ALA3526580 | E2074 | CL | = | 1.97 | L/hr/kg | ALA3529247 | mL.min-1.kg-1 | Canis lupus familiaris | |||
5. | ALA3526580 | E2074 | CLH | = | 2 | L/hr/kg | ALA3529245 | mL.min-1.kg-1 | Macaca fascicularis | |||
6. | ALA3526580 | E2074 | Tmax | = | 2 | hr | ALA3529948 | hr | Macaca fascicularis | |||
7. | ALA3526580 | E2074 | solubility | > | 2 | mg/ml | ALA3528492 | ug.mL-1 | ||||
8. | ALA3526580 | E2074 | t1/2 | = | 2.2 | hr | ALA3529944 | hr | Macaca fascicularis | |||
9. | ALA3526580 | E2074 | Kp | = | 2.4 | ALA3528490 | ||||||
10. | ALA3526580 | E2074 | F | = | 2.6 | % | ALA3528779 | % | Rattus norvegicus | |||
11. | ALA3526580 | E2074 | t1/2 | = | 2.73 | hr | ALA3529950 | hr | Macaca fascicularis | |||
12. | ALA3526580 | E2074 | Ratio | = | 3.14 | ALA3528483 | Mus musculus | |||||
13. | ALA3526580 | E2074 | CLH | = | 3.19 | L/hr/kg | ALA3529049 | mL.min-1.kg-1 | Rattus norvegicus | |||
14. | ALA3526580 | E2074 | Vdss | = | 3.29 | L/Kg | ALA3529940 | L.kg-1 | Macaca fascicularis | |||
15. | ALA3526580 | E2074 | Vmax | = | 3.58 | nmol/min/mg | ALA3529039 | nmol/min/mg | ||||
16. | ALA3526580 | E2074 | CL | = | 3.6 | L/hr/kg | ALA3529246 | mL.min-1.kg-1 | Rattus norvegicus | |||
17. | ALA3526580 | E2074 | Ratio | = | 1 | ALA3529946 | Macaca fascicularis | |||||
18. | ALA3526580 | E2074 | Ratio | = | 4.5 | ALA3529952 | Macaca fascicularis | |||||
19. | ALA3526580 | E2074 | Ratio | = | 1 | ALA3529947 | Macaca fascicularis | |||||
20. | ALA3526580 | E2074 | F | = | 5.3 | % | ALA3528784 | % | Rattus norvegicus |