Activities

#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Comment	Assay	Assay Organism
1.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541619	metabolite_detected		Homo sapiens
2.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541620	metabolite_detected		Rattus norvegicus
3.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541621	metabolite_detected		Homo sapiens
4.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541622	metabolite_detected		Rattus norvegicus
5.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	PB		0		ALA3541635	Active	%
6.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug excretion	=	1.5	%	ALA3539501		%
7.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug excretion	=	0.3	%	ALA3539500		%
8.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug excretion	=	0.06	%	ALA3539506		%
9.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541623	metabolite_detected		Homo sapiens
10.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541624	metabolite_detected		Rattus norvegicus
11.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541625	metabolite_detected		Homo sapiens
12.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541626	metabolite_detected		Rattus norvegicus
13.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541627	metabolite_detected		Homo sapiens
14.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541628	metabolite_detected		Rattus norvegicus
15.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541629	metabolite_detected		Homo sapiens
16.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541630	metabolite_detected		Rattus norvegicus
17.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541631	metabolite_detected		Homo sapiens
18.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Drug metabolism		0		ALA3541632	metabolite_detected		Rattus norvegicus
19.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Retention_time	=	12.8	min	ALA3541615		min	Homo sapiens
20.	2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one	[14C]-RRx-001	Retention_time	=	12.8	min	ALA3541616		min	Rattus norvegicus

1.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541619

metabolite_detected

Homo sapiens

2.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541620

metabolite_detected

Rattus norvegicus

3.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541621

metabolite_detected

Homo sapiens

4.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541622

metabolite_detected

Rattus norvegicus

5.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

PB

0

ALA3541635

Active

%

6.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug excretion

=

1.5

%

ALA3539501

%

7.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug excretion

=

0.3

%

ALA3539500

%

8.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug excretion

=

0.06

%

ALA3539506

%

9.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541623

metabolite_detected

Homo sapiens

10.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541624

metabolite_detected

Rattus norvegicus

11.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541625

metabolite_detected

Homo sapiens

12.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541626

metabolite_detected

Rattus norvegicus

13.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541627

metabolite_detected

Homo sapiens

14.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541628

metabolite_detected

Rattus norvegicus

15.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541629

metabolite_detected

Homo sapiens

16.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541630

metabolite_detected

Rattus norvegicus

17.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541631

metabolite_detected

Homo sapiens

18.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Drug metabolism

0

ALA3541632

metabolite_detected

Rattus norvegicus

19.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Retention_time

=

12.8

min

ALA3541615

min

Homo sapiens

20.

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

[14C]-RRx-001

Retention_time

=

12.8

min

ALA3541616

min

Rattus norvegicus