| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3542362 | [14C]YM178, [14C]Mirabegron | Radiolabel recovery | = | 48.7 | % | ALA3528357 | % | ||||
| 2. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Radiolabel recovery | = | 89.2 | % | ALA3528356 | % | Homo sapiens | |||
| 3. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Radiolabel recovery | = | 55 | % | ALA3528353 | % | ||||
| 4. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Blood/Plasma ratio | = | 2 | ALA3528352 | ||||||
| 5. | ALA3542362 | [14C]YM178, [14C]Mirabegron | beta t1/2 | = | 30.5 | hr | ALA3528350 | hr | Homo sapiens | |||
| 6. | ALA3542362 | [14C]YM178, [14C]Mirabegron | AUC | = | 13896 | ng.hr/ml | ALA3528349 | ng.hr.mL-1 | Homo sapiens | |||
| 7. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Cmax | = | 777 | ng/ml | ALA3528348 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Homo sapiens | ||
| 8. | ALA3542362 | [14C]YM178, [14C]Mirabegron | beta t1/2 | = | 84.5 | hr | ALA3528346 | hr | ||||
| 9. | ALA3542362 | [14C]YM178, [14C]Mirabegron | beta t1/2 | = | 28.2 | hr | ALA3528342 | hr | Homo sapiens | |||
| 10. | ALA3542362 | [14C]YM178, [14C]Mirabegron | AUC | = | 10443 | ng.hr/ml | ALA3531777 | ng.hr.mL-1 | Homo sapiens | |||
| 11. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Tmax | = | 2.25 | hr | ALA3531775 | hr | Homo sapiens | |||
| 12. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Activity | 0 | ALA3531774 | Non-toxic | Homo sapiens | |||||
| 13. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Activity | 0 | ALA3531773 | Non-toxic | Homo sapiens | |||||
| 14. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Activity | 0 | ALA3531771 | Non-toxic | Homo sapiens | |||||
| 15. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Radiolabel recovery | 0 | ALA3528355 | Below limit of detection | ||||||
| 16. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Radiolabel recovery | > | 94 | % | ALA3531685 | % | ||||
| 17. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Radiolabel recovery | > | 94 | % | ALA3531684 | % | ||||
| 18. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Radiolabel recovery | > | 94 | % | ALA3531683 | % | ||||
| 19. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Radiolabel recovery | > | 94 | % | ALA3531682 | % | ||||
| 20. | ALA3542362 | [14C]YM178, [14C]Mirabegron | Radiolabel recovery | = | 29.3 | % | ALA3534537 | % |
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