# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | AT13148 | AT-13148 | Inhibition | = | -6.76 | % | ALA4303805 | % | Severe acute respiratory syndrome coronavirus 2 | |||
2. | AT13148 | AT-13148 | T/C | = | 36 | % | ALA4022209 | % | Homo sapiens | |||
3. | AT13148 | AT-13148 | IC50 | = | 38 | nM | ALA4022195 | 7.42 | nM | Homo sapiens | ||
4. | AT13148 | AT-13148 | IC50 | = | 402 | nM | ALA4022196 | 6.40 | nM | Homo sapiens | ||
5. | AT13148 | AT-13148 | IC50 | = | 50 | nM | ALA4022197 | 7.30 | nM | Homo sapiens | ||
6. | AT13148 | AT-13148 | INH | > | 80 | % | ALA4022194 | % | ||||
7. | AT13148 | AT-13148 | INH | > | 80 | % | ALA4022198 | % | Rattus norvegicus | |||
8. | AT13148 | AT-13148 | INH | > | 80 | % | ALA4022199 | % | ||||
9. | AT13148 | AT-13148 | INH | > | 80 | % | ALA4022200 | % | Homo sapiens | |||
10. | AT13148 | AT-13148 | INH | > | 80 | % | ALA4022201 | % | ||||
11. | AT13148 | AT-13148 | INH | > | 80 | % | ALA4022202 | % | Homo sapiens | |||
12. | AT13148 | AT-13148 | INH | > | 80 | % | ALA4022203 | % | Homo sapiens | |||
13. | AT13148 | AT-13148 | IC50 | < | 10 | nM | ALA4022204 | nM | Homo sapiens | |||
14. | AT13148 | AT-13148 | Ratio IC50 | = | 10 | ALA4022205 | ||||||
15. | AT13148 | AT-13148 | t1/2 | = | 2.8 | hr | ALA4022206 | hr | Mus musculus | |||
16. | AT13148 | AT-13148 | Ratio | = | 13.6 | ALA4022207 | ||||||
17. | AT13148 | AT-13148 | INH | = | 50 | % | ALA4022208 | % | Homo sapiens | |||
18. | AT13148 | AT-13148 | Kd apparent | > | 30000 | nM | ALA3991926 | Inactive | nM | Homo sapiens | ||
19. | AT13148 | AT-13148 | Kd apparent | > | 30000 | nM | ALA3991925 | Inactive | nM | Homo sapiens | ||
20. | AT13148 | AT-13148 | Kd apparent | > | 30000 | nM | ALA3991924 | Inactive | nM | Homo sapiens |