# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3577298 | SAHA-TAP | Ki(app) | = | 7 | uM | ALA3578553 | 5.16 | nM | Homo sapiens | ||
2. | ALA3577298 | SAHA-TAP | EC50 | = | 9.37 | uM | ALA3578565 | 5.03 | nM | |||
3. | ALA3577298 | SAHA-TAP | EC50 | = | 6.05 | uM | ALA3578564 | 5.22 | nM | Homo sapiens | ||
4. | ALA3577298 | SAHA-TAP | EC50 | = | 3.38 | uM | ALA3578562 | 5.47 | nM | Homo sapiens | ||
5. | ALA3577298 | SAHA-TAP | Drug degradation | = | 23 | % | ALA3578560 | % | Homo sapiens | |||
6. | ALA3577298 | SAHA-TAP | Stability | = | 52 | % | ALA3578559 | % | Homo sapiens | |||
7. | ALA3577298 | SAHA-TAP | Stability | = | 72 | % | ALA3578558 | % | Homo sapiens | |||
8. | ALA3577298 | SAHA-TAP | K1/2 | = | 8 | uM | ALA3578556 | uM | Homo sapiens | |||
9. | ALA3577298 | SAHA-TAP | Ki | = | 250 | nM | ALA3578555 | 6.60 | nM | Homo sapiens | ||
10. | ALA3577298 | SAHA-TAP | INH | > | 90 | % | ALA3578554 | % | Homo sapiens | |||
11. | ALA3577298 | SAHA-TAP | INH | 0 | ALA3578553 | tde | % | Homo sapiens | ||||
12. | ALA3577298 | SAHA-TAP | INH | 0 | ALA3578552 | Active | % | Homo sapiens | ||||
13. | ALA3577298 | SAHA-TAP | Retention_time | = | 88.5 | min | ALA3578551 | min | Homo sapiens | |||
14. | ALA3577298 | SAHA-TAP | Stability | > | 95 | % | ALA3578550 | % | ||||
15. | ALA3577298 | SAHA-TAP | Stability | > | 95 | % | ALA3578549 | % | Bos taurus | |||
16. | ALA3577298 | SAHA-TAP | IC50(app) | = | 3842 | nM | ALA3578548 | 5.42 | nM | Homo sapiens | ||
17. | ALA3577298 | SAHA-TAP | IC50(app) | = | 23 | nM | ALA3578547 | 7.64 | nM | Homo sapiens | ||
18. | ALA3577298 | SAHA-TAP | Stability | > | 97 | % | ALA3578543 | % | ||||
19. | ALA3577298 | SAHA-TAP | IC50(app) | = | 371 | nM | ALA3578544 | 6.43 | nM | Homo sapiens | ||
20. | ALA3577298 | SAHA-TAP | IC50(app) | = | 255 | nM | ALA3578545 | 6.59 | nM | Homo sapiens |