# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3582469 | 23 | INH | 0 | ALA3583963 | Not Active | % | Rattus norvegicus | ||||
2. | ALA3582469 | 23 | INH | 0 | ALA3583962 | Active | % | |||||
3. | ALA3582469 | 23 | CL | = | 43 | ml/min.kg | ALA3583944 | mL.min-1.kg-1 | Rattus norvegicus | |||
4. | ALA3582469 | 23 | AUC/dose | = | 1.32 | uM.hr.kg/mg | ALA3583943 | uM.hr.kg/mg | Rattus norvegicus | |||
5. | ALA3582469 | 23 | F | = | 92 | % | ALA3583836 | % | Rattus norvegicus | |||
6. | ALA3582469 | 23 | CLH | < | 20 | ml/min.kg | ALA3583835 | mL.min-1.kg-1 | Rattus norvegicus | |||
7. | ALA3582469 | 23 | Fu | = | 15 | % | ALA3583834 | Rattus norvegicus | ||||
8. | ALA3582469 | 23 | Ratio IC50 | = | 176 | ALA3583833 | ||||||
9. | ALA3582469 | 23 | IC50 | = | 370 | nM | ALA3583832 | 6.43 | nM | Homo sapiens | ||
10. | ALA3582469 | 23 | IC50 | = | 2.1 | nM | ALA3583831 | 8.68 | nM | Homo sapiens |