# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3582481 | 35 | INH | 0 | ALA3583963 | Not Active | % | Rattus norvegicus | ||||
2. | ALA3582481 | 35 | INH | 0 | ALA3583962 | Active | % | |||||
3. | ALA3582481 | 35 | CL | = | 19 | ml/min.kg | ALA3583960 | mL.min-1.kg-1 | Macaca mulatta | |||
4. | ALA3582481 | 35 | AUC/dose | = | 2.49 | uM.hr.kg/mg | ALA3583959 | uM.hr.kg/mg | Macaca mulatta | |||
5. | ALA3582481 | 35 | F | = | 88 | % | ALA3583958 | % | Macaca mulatta | |||
6. | ALA3582481 | 35 | CLH | < | 20 | ml/min.kg | ALA3583957 | mL.min-1.kg-1 | ||||
7. | ALA3582481 | 35 | Fu | 0 | ALA3583956 | Not Determined | Macaca mulatta | |||||
8. | ALA3582481 | 35 | Ratio IC50 | > | 1000 | ALA3583952 | ||||||
9. | ALA3582481 | 35 | Ratio IC50 | > | 1000 | ALA3583951 | ||||||
10. | ALA3582481 | 35 | Ratio IC50 | > | 1000 | ALA3583950 | ||||||
11. | ALA3582481 | 35 | Ratio IC50 | = | 500 | ALA3583949 | ||||||
12. | ALA3582481 | 35 | IC50 | = | 8235 | nM | ALA3583946 | 5.08 | nM | Homo sapiens | ||
13. | ALA3582481 | 35 | IC50 | > | 10000 | nM | ALA3583945 | nM | Homo sapiens | |||
14. | ALA3582481 | 35 | IC50 | 0 | ALA3583830 | Not Determined | Homo sapiens | |||||
15. | ALA3582481 | 35 | IC50 | > | 10000 | nM | ALA3583829 | nM | Homo sapiens | |||
16. | ALA3582481 | 35 | Ratio IC50 | = | 553 | ALA3583833 | ||||||
17. | ALA3582481 | 35 | IC50 | = | 258 | nM | ALA3583832 | 6.59 | nM | Homo sapiens | ||
18. | ALA3582481 | 35 | IC50 | = | 0.5 | nM | ALA3583831 | 9.30 | nM | Homo sapiens |