| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3589039 | EPZ020411 | inhibition | = | -0.06 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 2. | ALA3589039 | EPZ020411 | inhibition | = | -0.15 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 3. | ALA3589039 | EPZ020411 | Inhibition | = | 11.431 | % | ALA4495582 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 4. | ALA3589039 | EPZ020411 | Inhibition | = | 10.64 | % | ALA4495582 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 5. | ALA3589039 | EPZ020411 | inhibition | = | -0.15 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 6. | ALA3589039 | EPZ020411 | inhibition | = | -0.06 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 7. | ALA3589039 | EPZ020411 | inhibition | = | 0.91 | % | ALA4808150 | % | Homo sapiens | |||
| 8. | ALA3589039 | EPZ020411 | inhibition | = | -22.95 | % | ALA4808149 | % | Homo sapiens | |||
| 9. | ALA3589039 | EPZ020411 | Inhibition | = | 3.91 | % | ALA4303805 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 10. | ALA3589039 | EPZ020411 | INH | 0 | ALA3784638 | Active | % | Homo sapiens | ||||
| 11. | ALA3589039 | EPZ020411 | INH | 0 | ALA3591656 | Dose-dependent effect | % | Homo sapiens | ||||
| 12. | ALA3589039 | EPZ020411 | Time | = | 12 | hr | ALA3591675 | hr | Rattus norvegicus | |||
| 13. | ALA3589039 | EPZ020411 | F | = | 65.6 | % | ALA3591674 | % | Rattus norvegicus | |||
| 14. | ALA3589039 | EPZ020411 | AUC | = | 2775 | hr.ng/ml | ALA3591673 | ng.hr.mL-1 | Rattus norvegicus | |||
| 15. | ALA3589039 | EPZ020411 | AUCt | = | 2456 | hr.ng/ml | ALA3591672 | ng.hr.mL-1 | Rattus norvegicus | |||
| 16. | ALA3589039 | EPZ020411 | Cmax | = | 844 | ng/ml | ALA3591671 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 17. | ALA3589039 | EPZ020411 | Tmax | = | 0.444 | hr | ALA3591670 | hr | Rattus norvegicus | |||
| 18. | ALA3589039 | EPZ020411 | beta t1/2 | = | 9.19 | hr | ALA3591669 | hr | Rattus norvegicus | |||
| 19. | ALA3589039 | EPZ020411 | AUC | = | 846 | hr.ng/ml | ALA3591668 | ng.hr.mL-1 | Rattus norvegicus | |||
| 20. | ALA3589039 | EPZ020411 | AUCt | = | 745 | hr.ng/ml | ALA3591667 | ng.hr.mL-1 | Rattus norvegicus |
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