| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  JAK3-IN-1 | 9 | Activity | 0 | ALA3602161 | Not Active | Mus musculus | |||||
| 2. | JAK3-IN-1 | 9 | Activity | 0 | ALA3602167 | Active | Mus musculus | |||||
| 3. | JAK3-IN-1 | 9 | Activity | 0 | ALA3602166 | Not Active | Mus musculus | |||||
| 4. | JAK3-IN-1 | 9 | Activity | 0 | ALA3602165 | Not Active | Mus musculus | |||||
| 5. | JAK3-IN-1 | 9 | Activity | 0 | ALA3602158 | Not Active | Mus musculus | |||||
| 6. | JAK3-IN-1 | 9 | Activity | 0 | ALA3602163 | Active | Homo sapiens | |||||
| 7. | JAK3-IN-1 | 9 | F | = | 66 | % | ALA3602156 | % | Mus musculus | |||
| 8. | JAK3-IN-1 | 9 | AUClast | = | 795.29 | hr/ng/ml | ALA3602093 | ng.hr.mL-1 | Mus musculus | |||
| 9. | JAK3-IN-1 | 9 | Cmax | = | 204.25 | ng/ml | ALA3602092 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 10. | JAK3-IN-1 | 9 | Tmax | = | 0.5 | hr | ALA3602091 | hr | Mus musculus | |||
| 11. | JAK3-IN-1 | 9 | Vdss | = | 18.38 | L/Kg | ALA3602090 | L.kg-1 | Mus musculus | |||
| 12. | JAK3-IN-1 | 9 | CL | = | 135.88 | ml/min.kg | ALA3602089 | mL.min-1.kg-1 | Mus musculus | |||
| 13. | JAK3-IN-1 | 9 | beta t1/2 | = | 1.4 | hr | ALA3602088 | hr | Mus musculus | |||
| 14. | JAK3-IN-1 | 9 | AUClast | = | 241.3 | hr/ng/ml | ALA3602087 | ng.hr.mL-1 | Mus musculus | |||
| 15. | JAK3-IN-1 | 9 | Cmax | = | 158.56 | ng/ml | ALA3602086 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 16. | JAK3-IN-1 | 9 | IC50 | = | 3047 | nM | ALA3603331 | 5.52 | nM | |||
| 17. | JAK3-IN-1 | 9 | IC50 | = | 2266 | nM | ALA3603330 | 5.64 | nM | |||
| 18. | JAK3-IN-1 | 9 | IC50 | = | 69 | nM | ALA3603329 | 7.16 | nM | |||
| 19. | JAK3-IN-1 | 9 | IC50 | = | 3194 | nM | ALA3603328 | 5.50 | nM | |||
| 20. | JAK3-IN-1 | 9 | IC50 | = | 3124 | nM | ALA3603327 | 5.50 | nM |
The page will load shortly, Thanks for your patience!