# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3608741 | 18 | IC50 | = | 50000 | nM | ALA3888930 | 4.30 | 423442 | nM | Homo sapiens | |
2. | ALA3608741 | 18 | Ki | > | 30000 | nM | ALA3888929 | 423398 | nM | Homo sapiens | ||
3. | ALA3608741 | 18 | Ki | = | 22000 | nM | ALA3888928 | 4.66 | 423354 | nM | Homo sapiens | |
4. | ALA3608741 | 18 | Ki | = | 32 | nM | ALA3888927 | 7.50 | 423307 | nM | Homo sapiens | |
5. | ALA3608741 | 18 | IC50 | = | 73 | nM | ALA3888926 | 7.14 | 423260 | nM | Homo sapiens | |
6. | ALA3608741 | 18 | Ratio | = | 0.18 | ALA3610294 | ||||||
7. | ALA3608741 | 18 | Ratio | = | 3.89 | ALA3610292 | ||||||
8. | ALA3608741 | 18 | Ratio | = | 1.82 | ALA3610115 | ||||||
9. | ALA3608741 | 18 | Ratio | = | 38.9 | ALA3610113 | ||||||
10. | ALA3608741 | 18 | Tmax | = | 45 | min | ALA3610111 | hr | Rattus norvegicus | |||
11. | ALA3608741 | 18 | MED | = | 10 | mg kg-1 | ALA3610109 | mg kg-1 | Rattus norvegicus | |||
12. | ALA3608741 | 18 | Ki | = | 244 | nM | ALA3610107 | 6.61 | nM | Rattus norvegicus | ||
13. | ALA3608741 | 18 | F | = | 46.6 | % | ALA3610105 | % | Rattus norvegicus | |||
14. | ALA3608741 | 18 | t1/2 | = | 215 | min | ALA3610103 | hr | Rattus norvegicus | |||
15. | ALA3608741 | 18 | Vdss | = | 1.59 | L/Kg | ALA3610101 | L.kg-1 | Rattus norvegicus | |||
16. | ALA3608741 | 18 | CL | = | 5.07 | min/ml/kg | ALA3610099 | min/ml/kg | Rattus norvegicus | |||
17. | ALA3608741 | 18 | BPR | = | 0.05 | ALA3610098 | ||||||
18. | ALA3608741 | 18 | Drug uptake(free) | = | 45.6 | nM | ALA3610097 | nM | Rattus norvegicus | |||
19. | ALA3608741 | 18 | Cp(f) | = | 897.4 | nM | ALA3610095 | nM | Rattus norvegicus | |||
20. | ALA3608741 | 18 | Fu | = | 0.995 | ALA3610094 | Rattus norvegicus |