# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3613349 | 43c | Ratio | = | 104 | ALA3616193 | ||||||
2. | ALA3613349 | 43c | Ratio | = | 434 | ALA3616192 | ||||||
3. | ALA3613349 | 43c | Drug uptake | = | 22.2 | ug/g | ALA3616191 | ug/g | ||||
4. | ALA3613349 | 43c | Drug uptake | = | 93 | ug/g | ALA3616190 | ug/g | ||||
5. | ALA3613349 | 43c | Cp | = | 0.21 | ug ml-1 | ALA3616188 | ug ml-1 | Mus musculus | |||
6. | ALA3613349 | 43c | F | = | 13.4 | % | ALA3616189 | % | Rattus norvegicus | |||
7. | ALA3613349 | 43c | AUC | = | 0.24 | microg.hr/mL | ALA3616187 | ng.hr.mL-1 | Rattus norvegicus | |||
8. | ALA3613349 | 43c | t1/2 | = | 1.71 | hr | ALA3616186 | hr | Rattus norvegicus | |||
9. | ALA3613349 | 43c | Cmax | = | 0.12 | ug ml-1 | ALA3616185 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
10. | ALA3613349 | 43c | Tmax | = | 1.17 | hr | ALA3616184 | hr | Rattus norvegicus | |||
11. | ALA3613349 | 43c | Vdss | = | 3.47 | L/Kg | ALA3616183 | L.kg-1 | Rattus norvegicus | |||
12. | ALA3613349 | 43c | CL | = | 2.71 | L/kg/hr | ALA3616182 | mL.min-1.kg-1 | Rattus norvegicus | |||
13. | ALA3613349 | 43c | AUC | = | 1.85 | microg.hr/mL | ALA3616181 | ng.hr.mL-1 | Rattus norvegicus | |||
14. | ALA3613349 | 43c | t1/2 | = | 1.07 | hr | ALA3616180 | hr | Rattus norvegicus | |||
15. | ALA3613349 | 43c | IC50 | > | 100 | uM | ALA3616179 | nM | ||||
16. | ALA3613349 | 43c | IC50 | > | 100 | uM | ALA3616178 | nM | Homo sapiens | |||
17. | ALA3613349 | 43c | IC50 | > | 100 | uM | ALA3616177 | nM | Mus musculus | |||
18. | ALA3613349 | 43c | IC50 | > | 100 | uM | ALA3616176 | nM | ||||
19. | ALA3613349 | 43c | IC50 | > | 100 | uM | ALA3616175 | nM | Chlorocebus sabaeus | |||
20. | ALA3613349 | 43c | permeability | = | -4.72 | ALA3616174 |