Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	PF-06471553	6f	Activity		0		ALA3614522		Not Active		Mus musculus
2.	PF-06471553	6f	IC50	=	4	uM	ALA3614523	5.40		nM	Homo sapiens
3.	PF-06471553	6f	Activity		0		ALA3614424		Non-toxic
4.	PF-06471553	6f	INH		0		ALA3614423		Active	%	Mus musculus
5.	PF-06471553	6f	Activity		0		ALA3614422		Not Active		Mus musculus
6.	PF-06471553	6f	INH		0		ALA3614421		Not Active	%	Mus musculus
7.	PF-06471553	6f	AUClast	=	27	microg.hr/mL	ALA3614420			ng.hr.mL-1	Mus musculus
8.	PF-06471553	6f	Cmax	=	9.3	ug ml-1	ALA3614419		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Mus musculus
9.	PF-06471553	6f	F	=	74	%	ALA3614418			%	Mus musculus
10.	PF-06471553	6f	t1/2	=	1.4	hr	ALA3614417			hr	Mus musculus
11.	PF-06471553	6f	Vd	=	0.17	L/Kg	ALA3614416			L.kg-1	Mus musculus
12.	PF-06471553	6f	CL	=	1.4	ml/min.kg	ALA3614415			mL.min-1.kg-1	Mus musculus
13.	PF-06471553	6f	Ratio IC50	>	160		ALA3614414
14.	PF-06471553	6f	Ratio IC50	>	160		ALA3614413
15.	PF-06471553	6f	Ratio IC50	>	160		ALA3616261
16.	PF-06471553	6f	Ratio IC50	>	160		ALA3616260
17.	PF-06471553	6f	Activity		0		ALA3616259		Non-toxic		Homo sapiens
18.	PF-06471553	6f	Activity		0		ALA3616258		Non-toxic		Salmonella enterica subsp. enterica serovar Typhimurium
19.	PF-06471553	6f	INH		0		ALA3616257		Not Active	%	Homo sapiens
20.	PF-06471553	6f	INH		0		ALA3616256		Not Active	%	Homo sapiens