# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3617078 | 61 | Activity | = | 1.2 | mM | ALA3619637 | mM | Mus musculus | |||
2. | ALA3617078 | 61 | INH | 0 | ALA3619636 | Dose-dependent effect | % | Mus musculus | ||||
3. | ALA3617078 | 61 | INH | 0 | ALA3619635 | Dose-dependent effect | % | Mus musculus | ||||
4. | ALA3617078 | 61 | INH | 0 | ALA3619128 | Dose-dependent effect | % | Mus musculus | ||||
5. | ALA3617078 | 61 | Activity | 0 | ALA3619126 | Non-toxic | Mus musculus | |||||
6. | ALA3617078 | 61 | Activity | 0 | ALA3618987 | Non-toxic | Mus musculus | |||||
7. | ALA3617078 | 61 | INH | 0 | ALA3618985 | Active | % | Mus musculus | ||||
8. | ALA3617078 | 61 | INH | 0 | ALA3618983 | Active | % | Mus musculus | ||||
9. | ALA3617078 | 61 | INH | 0 | ALA3618981 | Active | % | Mus musculus | ||||
10. | ALA3617078 | 61 | PPB | = | 97 | % | ALA3618980 | % | ||||
11. | ALA3617078 | 61 | F | = | 100 | % | ALA3618979 | % | Mus musculus | |||
12. | ALA3617078 | 61 | CL | = | 0.3 | ml/min.kg | ALA3618978 | mL.min-1.kg-1 | Mus musculus | |||
13. | ALA3617078 | 61 | t1/2 | = | 9.2 | hr | ALA3618977 | hr | Mus musculus | |||
14. | ALA3617078 | 61 | AUCt | = | 306 | ug.hr/ml | ALA3618976 | ng.hr.mL-1 | Mus musculus | |||
15. | ALA3617078 | 61 | BBR | = | 0.03 | ALA3618975 | ||||||
16. | ALA3617078 | 61 | pIC50 | = | 6.6 | ALA3618972 | 6.60 | nM | Homo sapiens | |||
17. | ALA3617078 | 61 | pIC50 | = | 6.8 | ALA3618965 | 6.80 | nM | Homo sapiens | |||
18. | ALA3617078 | 61 | Kinetic_solubility | = | 164 | ug ml-1 | ALA3618964 | ug.mL-1 | ||||
19. | ALA3617078 | 61 | logD | = | 3.12 | ALA3618963 | ||||||
20. | ALA3617078 | 61 | pIC50 | = | 7.3 | ALA3618962 | 7.30 | nM | Homo sapiens |