# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3618201 | 14 | Stability | = | 74 | % | ALA3762859 | % | Rattus norvegicus | |||
2. | ALA3618201 | 14 | Stability | = | 94 | % | ALA3762858 | % | Rattus norvegicus | |||
3. | ALA3618201 | 14 | Cmax | = | 11 | ng/ml | ALA3762857 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
4. | ALA3618201 | 14 | AUC | = | 40 | ng.hr/ml | ALA3762856 | ng.hr.mL-1 | Rattus norvegicus | |||
5. | ALA3618201 | 14 | IC50 | = | 6.2 | nM | ALA3762854 | 8.21 | nM | Homo sapiens | ||
6. | ALA3618201 | 14 | IC50 | = | 6.2 | nM | ALA3705665 | 8.21 | 288373 | nM | Homo sapiens | |
7. | ALA3618201 | 14 | IC50 | = | 3.3 | nM | ALA3707512 | 8.48 | 288382 | nM | Rattus norvegicus | |
8. | ALA3618201 | 14 | permeability | = | 18 | 10'-6 cm/s | ALA3619061 | 10'-6 cm/s | Homo sapiens | |||
9. | ALA3618201 | 14 | permeability | = | 1.3 | 10'-6 cm/s | ALA3619060 | 10'-6 cm/s | Homo sapiens | |||
10. | ALA3618201 | 14 | PB | = | 99.8 | % | ALA3619059 | % | Homo sapiens | |||
11. | ALA3618201 | 14 | solubility | = | 0.051 | mg/ml | ALA3619058 | ug.mL-1 | ||||
12. | ALA3618201 | 14 | IC50 | > | 10 | uM | ALA3619057 | nM | Homo sapiens | |||
13. | ALA3618201 | 14 | IC50 | > | 10 | uM | ALA3619056 | nM | Homo sapiens | |||
14. | ALA3618201 | 14 | IC50 | > | 10 | uM | ALA3619055 | nM | Homo sapiens | |||
15. | ALA3618201 | 14 | IC50 | > | 10 | uM | ALA3619054 | nM | Homo sapiens | |||
16. | ALA3618201 | 14 | PB | = | 99.6 | % | ALA3619053 | % | Rattus norvegicus | |||
17. | ALA3618201 | 14 | CL | = | 18 | ml/min.kg | ALA3619052 | mL.min-1.kg-1 | Rattus norvegicus | |||
18. | ALA3618201 | 14 | IC50 | = | 124 | uM | ALA3619050 | nM | Homo sapiens | |||
19. | ALA3618201 | 14 | Ratio IC50 | = | 1.9 | ALA3619049 | ||||||
20. | ALA3618201 | 14 | Stability | = | 96 | % | ALA3619048 | % | Rattus norvegicus |