# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3622442 | 14 | INH | 0 | ALA3625365 | Active | % | Rattus norvegicus | ||||
2. | ALA3622442 | 14 | IC50 | = | 34 | nM | ALA3625364 | 7.47 | nM | |||
3. | ALA3622442 | 14 | PPB | = | 67 | % | ALA3625354 | % | Rattus norvegicus | |||
4. | ALA3622442 | 14 | t1/2 | = | 1.5 | hr | ALA3625350 | hr | Rattus norvegicus | |||
5. | ALA3622442 | 14 | CL | = | 50 | ml/min.kg | ALA3625349 | mL.min-1.kg-1 | Rattus norvegicus | |||
6. | ALA3622442 | 14 | AUC/dose | = | 0.19 | uM.hr.Kg/mg | ALA3625348 | uM.hr.Kg/mg | Rattus norvegicus | |||
7. | ALA3622442 | 14 | F | = | 19 | % | ALA3625347 | % | Rattus norvegicus | |||
8. | ALA3622442 | 14 | CLH | < | 20 | ml/min.kg | ALA3625233 | mL.min-1.kg-1 | Rattus norvegicus | |||
9. | ALA3622442 | 14 | logD | = | 0.6 | ALA3625232 | ||||||
10. | ALA3622442 | 14 | Ratio IC50 | = | 29 | ALA3625231 | ||||||
11. | ALA3622442 | 14 | IC50 | > | 8333 | nM | ALA3624351 | nM | Homo sapiens | |||
12. | ALA3622442 | 14 | IC50 | = | 283 | nM | ALA3624350 | 6.55 | nM | Homo sapiens |