# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3622826 | 5c | log Pe | = | -5.12 | ALA3817419 | ||||||
2. | ALA3622826 | 5c | IC50 | = | 0.05 | uM | ALA3817420 | 7.30 | nM | Mus musculus | ||
3. | ALA3622826 | 5c | IC50 | = | 3.2 | uM | ALA3817421 | 5.50 | nM | Homo sapiens | ||
4. | ALA3622826 | 5c | IC50 | = | 1.3 | uM | ALA3817422 | 5.89 | nM | Homo sapiens | ||
5. | ALA3622826 | 5c | IC50 | = | 3.7 | uM | ALA3817423 | 5.43 | nM | Homo sapiens | ||
6. | ALA3622826 | 5c | Ratio IC50 | = | 63 | ALA3817424 | ||||||
7. | ALA3622826 | 5c | Ratio IC50 | = | 25 | ALA3817425 | ||||||
8. | ALA3622826 | 5c | Ratio IC50 | = | 74 | ALA3817426 | ||||||
9. | ALA3622826 | 5c | INH | 0 | ALA3624091 | Not Active | % | Homo sapiens | ||||
10. | ALA3622826 | 5c | INH | 0 | ALA3624090 | Not Active | % | Homo sapiens | ||||
11. | ALA3622826 | 5c | t1/2 | = | 9.1 | hr | ALA3624089 | hr | Rattus norvegicus | |||
12. | ALA3622826 | 5c | CL | = | 0.4 | L/hr/kg | ALA3624088 | mL.min-1.kg-1 | Rattus norvegicus | |||
13. | ALA3622826 | 5c | Vdss | = | 0.5 | L/Kg | ALA3624087 | L.kg-1 | Rattus norvegicus | |||
14. | ALA3622826 | 5c | F | = | 0.7 | % | ALA3624086 | % | Rattus norvegicus | |||
15. | ALA3622826 | 5c | permeability | = | 0.1 | 10'-6 cm/s | ALA3624085 | 10'-6 cm/s | ||||
16. | ALA3622826 | 5c | Activity | > | 65 | % | ALA3624084 | % | Homo sapiens | |||
17. | ALA3622826 | 5c | Activity | > | 65 | % | ALA3624083 | % | Homo sapiens | |||
18. | ALA3622826 | 5c | Activity | > | 65 | % | ALA3624082 | % | Homo sapiens | |||
19. | ALA3622826 | 5c | Activity | > | 65 | % | ALA3624081 | % | Homo sapiens | |||
20. | ALA3622826 | 5c | Activity | > | 65 | % | ALA3624080 | % | Homo sapiens |