Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA3623830	(+)-(R)-6	solubility	=	315	ug ml-1	ALA3626126			ug.mL-1
2.	ALA3623830	(+)-(R)-6	permeability	=	4.8	ucm/s	ALA3624658			ucm/s
3.	ALA3623830	(+)-(R)-6	logD	=	2.2		ALA3626125
4.	ALA3623830	(+)-(R)-6	INH	<	10	%	ALA3624680			%	Macaca fascicularis
5.	ALA3623830	(+)-(R)-6	Activity		0		ALA3624679		Active		Macaca fascicularis
6.	ALA3623830	(+)-(R)-6	Activity		0		ALA3624678		Not Active		Macaca fascicularis
7.	ALA3623830	(+)-(R)-6	Activity		0		ALA3624674		Dose-dependent effect		Macaca fascicularis
8.	ALA3623830	(+)-(R)-6	Activity		0		ALA3624670		Active		Rattus norvegicus
9.	ALA3623830	(+)-(R)-6	Activity		0		ALA3624669		Active		Rattus norvegicus
10.	ALA3623830	(+)-(R)-6	Activity		0		ALA3624668		Active		Rattus norvegicus
11.	ALA3623830	(+)-(R)-6	Activity		0		ALA3624667		Active		Rattus norvegicus
12.	ALA3623830	(+)-(R)-6	Activity		0		ALA3624661		Not Active		Mus musculus
13.	ALA3623830	(+)-(R)-6	Activity		0		ALA3624659		Dose-dependent effect		Mus musculus
14.	ALA3623830	(+)-(R)-6	IC50	>	50	uM	ALA3626124			nM	Homo sapiens
15.	ALA3623830	(+)-(R)-6	IC50	>	50	uM	ALA3626123			nM	Homo sapiens
16.	ALA3623830	(+)-(R)-6	IC50	>	50	uM	ALA3626122			nM	Homo sapiens
17.	ALA3623830	(+)-(R)-6	IC50	=	530	nM	ALA3626121	6.28		nM	Mus musculus
18.	ALA3623830	(+)-(R)-6	Ratio IC50	=	160		ALA3626120
19.	ALA3623830	(+)-(R)-6	IC50	=	3	nM	ALA3626119	8.52		nM
20.	ALA3623830	(+)-(R)-6	CL	<	10	ug/min	ALA3626118			ug/min