# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3629567 | VFV | IC50 | = | 0.8 | nM | ALA5246282 | 9.10 | nM | Trypanosoma cruzi | ||
2. | ALA3629567 | VFV | IC50 | = | 24.4 | uM | ALA4323745 | 4.61 | nM | Homo sapiens | ||
3. | ALA3629567 | VFV | INH | = | 33 | % | ALA4323744 | % | Homo sapiens | |||
4. | ALA3629567 | VFV | INH | = | 64 | % | ALA4323743 | % | Homo sapiens | |||
5. | ALA3629567 | VFV | IC50 | < | 0.5 | uM | ALA4323742 | nM | Homo sapiens | |||
6. | ALA3629567 | VFV | Kd | = | 0.09 | uM | ALA4323740 | 7.05 | nM | Homo sapiens | ||
7. | ALA3629567 | VFV | EC50 | = | 10 | uM | ALA4323739 | 5.00 | nM | Homo sapiens | ||
8. | ALA3629567 | VFV | EC50 | = | 10 | uM | ALA4323738 | 5.00 | nM | Homo sapiens | ||
9. | ALA3629567 | VFV | EC50 | = | 10 | uM | ALA4323737 | 5.00 | nM | Homo sapiens | ||
10. | ALA3629567 | VFV | EC50 | = | 10 | uM | ALA4323736 | 5.00 | nM | Homo sapiens | ||
11. | ALA3629567 | VFV | logP | = | 5.4 | ALA4323735 | ||||||
12. | ALA3629567 | VFV | Kd | = | 10 | nM | ALA5057939 | 8.00 | nM | |||
13. | ALA3629567 | VFV | IC50 | = | 5.94 | uM | ALA5057938 | 5.23 | nM | |||
14. | ALA3629567 | VFV | Activity | = | 89 | % | ALA3631890 | % | Leishmania | |||
15. | ALA3629567 | VFV | Activity | = | 100 | % | ALA3632434 | % | Trypanosoma cruzi | |||
16. | ALA3629567 | VFV | logP | = | 5.44 | ALA4261111 | ||||||
17. | ALA3629567 | VFV | EC50 | = | 1.5 | nM | ALA4261103 | 8.82 | nM | Trypanosoma cruzi | ||
18. | ALA3629567 | VFV | EC50 | = | 1 | nM | ALA4261102 | 9.00 | nM | Trypanosoma cruzi | ||
19. | ALA3629567 | VFV | Kd | = | 8.4 | nM | ALA4261101 | 8.08 | nM | Leishmania infantum | ||
20. | ALA3629567 | VFV | Kd | = | 6.8 | nM | ALA4261100 | 8.17 | nM | Trypanosoma cruzi (strain CL Brener) |