# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | PF 06281355 | 7 | inhibition | = | -0.22 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
2. | PF 06281355 | 7 | Inhibition | = | 11.01 | % | ALA4495582 | % | Severe acute respiratory syndrome coronavirus 2 | |||
3. | PF 06281355 | 7 | inhibition | = | -0.22 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
4. | PF 06281355 | 7 | INH | = | 57 | % | ALA5152353 | % | Homo sapiens | |||
5. | PF 06281355 | 7 | pKinact | = | 2.38 | ALA3636509 | Homo sapiens | |||||
6. | PF 06281355 | 7 | F | = | 100 | % | ALA3636545 | % | Canis lupus familiaris | |||
7. | PF 06281355 | 7 | F | = | 61 | % | ALA3636544 | % | Rattus norvegicus | |||
8. | PF 06281355 | 7 | Tmax | = | 0.63 | hr | ALA3636541 | hr | Canis lupus familiaris | |||
9. | PF 06281355 | 7 | Tmax | = | 0.67 | hr | ALA3636540 | hr | Rattus norvegicus | |||
10. | PF 06281355 | 7 | beta t1/2 | = | 2.8 | hr | ALA3636537 | hr | Canis lupus familiaris | |||
11. | PF 06281355 | 7 | beta t1/2 | = | 0.38 | hr | ALA3636536 | hr | Rattus norvegicus | |||
12. | PF 06281355 | 7 | Vdss | = | 1.03 | L/Kg | ALA3636533 | L.kg-1 | Canis lupus familiaris | |||
13. | PF 06281355 | 7 | Vdss | = | 0.83 | L/Kg | ALA3636532 | L.kg-1 | Rattus norvegicus | |||
14. | PF 06281355 | 7 | CL | = | 7.07 | ml/min.kg | ALA3636529 | mL.min-1.kg-1 | Canis lupus familiaris | |||
15. | PF 06281355 | 7 | CL | = | 37.6 | ml/min.kg | ALA3636528 | mL.min-1.kg-1 | Rattus norvegicus | |||
16. | PF 06281355 | 7 | CLH(app) | < | 6 | uL/min | ALA3636527 | uL/min | Homo sapiens | |||
17. | PF 06281355 | 7 | CLH(app) | < | 8 | uL/min/ug | ALA3636526 | mL.min-1.g-1 | Homo sapiens | |||
18. | PF 06281355 | 7 | Fu | = | 0.6 | ALA3636525 | Homo sapiens | |||||
19. | PF 06281355 | 7 | Papp | = | 1.1 | ucm/s | ALA3636521 | ucm/s | ||||
20. | PF 06281355 | 7 | Drug metabolism | 0 | ALA3636524 | metabolite_notdetected |