| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3634745 | 18b | IC50 | > | 1200 | nM | ALA3637062 | nM | Homo sapiens | |||
| 2. | ALA3634745 | 18b | Drug metabolism | 0 | ALA3637056 | metabolite_detected | ||||||
| 3. | ALA3634745 | 18b | Drug metabolism | 0 | ALA3637055 | metabolite_detected | ||||||
| 4. | ALA3634745 | 18b | INH | = | 42.4 | % | ALA3637054 | % | Homo sapiens | |||
| 5. | ALA3634745 | 18b | Ratio IC50 | = | 135 | ALA3637053 | ||||||
| 6. | ALA3634745 | 18b | IC50 | = | 220 | nM | ALA3637052 | 6.66 | nM | Homo sapiens | ||
| 7. | ALA3634745 | 18b | IC50 | > | 1200 | nM | ALA3637051 | nM | Homo sapiens | |||
| 8. | ALA3634745 | 18b | IC50 | > | 1200 | nM | ALA3637050 | nM | Homo sapiens | |||
| 9. | ALA3634745 | 18b | IC50 | = | 6.7 | nM | ALA3637049 | 8.17 | nM | Homo sapiens | ||
| 10. | ALA3634745 | 18b | solubility | < | 0.1 | ug ml-1 | ALA3636192 | ug.mL-1 | ||||
| 11. | ALA3634745 | 18b | permeability | = | 2.9 | ucm/s | ALA3636191 | ucm/s | ||||
| 12. | ALA3634745 | 18b | BPR | = | 1.1 | ALA3636190 | ||||||
| 13. | ALA3634745 | 18b | AUCt | = | 359 | ng.hr/ml | ALA3635703 | ng.hr.mL-1 | Rattus norvegicus | |||
| 14. | ALA3634745 | 18b | Tmax | = | 0.5 | hr | ALA3635702 | hr | Rattus norvegicus | |||
| 15. | ALA3634745 | 18b | Cmax | = | 44 | ng/ml | ALA3635701 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 16. | ALA3634745 | 18b | Stability | = | 74 | % | ALA3635700 | % | Homo sapiens | |||
| 17. | ALA3634745 | 18b | Stability | = | 49 | % | ALA3635699 | % | ||||
| 18. | ALA3634745 | 18b | Stability | = | 99 | % | ALA3635698 | % | Canis lupus familiaris | |||
| 19. | ALA3634745 | 18b | Stability | = | 54 | % | ALA3635697 | % | ||||
| 20. | ALA3634745 | 18b | Stability | = | 48.1 | % | ALA3635696 | % | Rattus norvegicus |
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