| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3651854 | BDBM107057 | IC50 | = | 20 | nM | ALA3705165 | 7.70 | 226269 | nM | Homo sapiens | |
| 2. | ALA3651854 | BDBM107057 | Ratio IC50 | = | 20 | ALA4716887 | ||||||
| 3. | ALA3651854 | BDBM107057 | IC50 | = | 26 | nM | ALA4716886 | 7.58 | nM | Homo sapiens | ||
| 4. | ALA3651854 | BDBM107057 | Activity | 0 | ALA4716885 | Non-Toxic | ||||||
| 5. | ALA3651854 | BDBM107057 | T/C | = | -54 | % | ALA4716884 | % | Homo sapiens | |||
| 6. | ALA3651854 | BDBM107057 | T/C | = | 37 | % | ALA4716883 | % | Homo sapiens | |||
| 7. | ALA3651854 | BDBM107057 | Activity | 0 | ALA4716882 | Dose-dependent effect | Homo sapiens | |||||
| 8. | ALA3651854 | BDBM107057 | F | = | 35 | % | ALA4716881 | % | ||||
| 9. | ALA3651854 | BDBM107057 | AUC | = | 3071 | hr.nM | ALA4716880 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 10. | ALA3651854 | BDBM107057 | Cmax | = | 151 | nM | ALA4716879 | nM | ||||
| 11. | ALA3651854 | BDBM107057 | Vdss | = | 19.4 | L/Kg | ALA4716878 | L.kg-1 | ||||
| 12. | ALA3651854 | BDBM107057 | CL | = | 32 | ml/min.kg | ALA4716877 | mL.min-1.kg-1 | ||||
| 13. | ALA3651854 | BDBM107057 | F | = | 58 | % | ALA4716876 | % | ||||
| 14. | ALA3651854 | BDBM107057 | AUC | = | 4899 | hr.nM | ALA4716875 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 15. | ALA3651854 | BDBM107057 | Cmax | = | 429 | nM | ALA4716874 | nM | ||||
| 16. | ALA3651854 | BDBM107057 | Vdss | = | 12.1 | L/Kg | ALA4716873 | L.kg-1 | ||||
| 17. | ALA3651854 | BDBM107057 | CL | = | 71 | ml/min.kg | ALA4716872 | mL.min-1.kg-1 | ||||
| 18. | ALA3651854 | BDBM107057 | IC50 | = | 20.8 | uM | ALA4716871 | 4.68 | nM | Homo sapiens | ||
| 19. | ALA3651854 | BDBM107057 | permeability | = | 3.3 | cm/s | ALA4716869 | cm/s | ||||
| 20. | ALA3651854 | BDBM107057 | permeability | = | 2.1 | cm/s | ALA4716868 | cm/s |
The page will load shortly, Thanks for your patience!