# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3662077 | BDBM145466 | IC50 | = | 4 | nM | ALA3705617 | 8.40 | 281981 | nM | Homo sapiens | |
2. | ALA3662077 | BDBM145466 | Activity | = | 84 | % | ALA5264253 | % | Mus musculus | |||
3. | ALA3662077 | BDBM145466 | Activity | = | 72 | % | ALA5264252 | % | Mus musculus | |||
4. | ALA3662077 | BDBM145466 | Activity | = | 56 | % | ALA5264251 | % | Mus musculus | |||
5. | ALA3662077 | BDBM145466 | F | = | 66 | % | ALA5264242 | % | ||||
6. | ALA3662077 | BDBM145466 | AUC | = | 160 | uM.hr | ALA5264241 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
7. | ALA3662077 | BDBM145466 | Cmax | = | 25 | uM | ALA5264240 | nM | ||||
8. | ALA3662077 | BDBM145466 | t1/2 | = | 16.9 | hr | ALA5264239 | hr | ||||
9. | ALA3662077 | BDBM145466 | Vdss | = | 0.29 | L/Kg | ALA5264238 | L.kg-1 | ||||
10. | ALA3662077 | BDBM145466 | CL | = | 0.4 | ml/min.kg | ALA5264237 | mL.min-1.kg-1 | ||||
11. | ALA3662077 | BDBM145466 | t1/2 | = | 9 | hr | ALA5264236 | hr | ||||
12. | ALA3662077 | BDBM145466 | F | = | 49 | % | ALA5264235 | % | ||||
13. | ALA3662077 | BDBM145466 | AUC | = | 350 | uM.hr | ALA5264234 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
14. | ALA3662077 | BDBM145466 | Cmax | = | 69 | uM | ALA5264233 | nM | ||||
15. | ALA3662077 | BDBM145466 | t1/2 | = | 15.6 | hr | ALA5264232 | hr | ||||
16. | ALA3662077 | BDBM145466 | Vdss | = | 0.28 | L/Kg | ALA5264231 | L.kg-1 | ||||
17. | ALA3662077 | BDBM145466 | CL | = | 1.6 | ml/min.kg | ALA5264230 | mL.min-1.kg-1 | ||||
18. | ALA3662077 | BDBM145466 | t1/2 | = | 2.1 | hr | ALA5264229 | hr | ||||
19. | ALA3662077 | BDBM145466 | Ratio | = | 56 | ALA5264226 | ||||||
20. | ALA3662077 | BDBM145466 | Papp | = | 0.4 | 10^-6 cm/s | ALA5264225 | 10^-6 cm/s |