# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA333928 | 2 | pKa | = | 6.6 | ALA4703127 | ||||||
2. | ALA333928 | 2 | Fu | = | 13 | % | ALA4703117 | |||||
3. | ALA333928 | 2 | Fu | = | 0.6 | % | ALA4703116 | |||||
4. | ALA333928 | 2 | t1/2 | = | 2.4 | hr | ALA4703115 | hr | ||||
5. | ALA333928 | 2 | AUC | = | 22.2 | uM.hr | ALA4703114 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
6. | ALA333928 | 2 | Cmax | = | 30.9 | uM | ALA4703113 | nM | ||||
7. | ALA333928 | 2 | IC50 | > | 10 | uM | ALA4703112 | nM | Homo sapiens | |||
8. | ALA333928 | 2 | IC50 | > | 10 | uM | ALA4703111 | nM | Homo sapiens | |||
9. | ALA333928 | 2 | IC50 | > | 10 | uM | ALA4703110 | nM | Homo sapiens | |||
10. | ALA333928 | 2 | IC50 | > | 10 | uM | ALA4703109 | nM | Homo sapiens | |||
11. | ALA333928 | 2 | IC50 | > | 10 | uM | ALA4703108 | nM | Homo sapiens | |||
12. | ALA333928 | 2 | permeability | = | 167 | nm/s | ALA4703107 | nm/s | ||||
13. | ALA333928 | 2 | permeability | = | 420 | nm/s | ALA4703106 | nm/s | ||||
14. | ALA333928 | 2 | Stabilty | = | 80 | % | ALA4703105 | % | ||||
15. | ALA333928 | 2 | Stabilty | = | 95 | % | ALA4703104 | % | ||||
16. | ALA333928 | 2 | Stabilty | = | 93 | % | ALA4703103 | % | ||||
17. | ALA333928 | 2 | t1/2 | = | 2.8 | hr | ALA4703102 | hr | ||||
18. | ALA333928 | 2 | INH | 0 | ALA4703101 | Active | % | Homo sapiens | ||||
19. | ALA333928 | 2 | IC50 | = | 0.103 | uM | ALA4703100 | 6.99 | nM | Homo sapiens | ||
20. | ALA333928 | 2 | IC50 | = | 0.105 | uM | ALA4703099 | 6.98 | nM | Homo sapiens |