# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA121896 | 18n | IC50 | = | 76 | nM | ALA5121348 | 7.12 | nM | Homo sapiens | ||
2. | ALA121896 | 18n | logD | = | 2.78 | ALA5121332 | ||||||
3. | ALA121896 | 18n | Therm_solubility | = | 10 | mg/ml | ALA5121331 | ug.mL-1 | ||||
4. | ALA121896 | 18n | IC50 | = | 76 | nM | ALA828240 | 7.12 | nM | Homo sapiens | ||
5. | ALA121896 | 18n | Ki | = | 3.4 | nM | ALA839639 | 8.47 | nM | Homo sapiens | ||
6. | ALA121896 | 18n | Ratio | = | 1.2 | ALA624653 | Rattus norvegicus | |||||
7. | ALA121896 | 18n | Bioavailabiility | = | 30.5 | % | ALA622901 | % | Rattus norvegicus | |||
8. | ALA121896 | 18n | AUC | = | 1472 | ng ml-1 hr-1 | ALA622911 | ng.hr.mL-1 | Rattus norvegicus | |||
9. | ALA121896 | 18n | AUC | = | 1182 | ng ml-1 hr-1 | ALA622914 | ng.hr.mL-1 | Rattus norvegicus | |||
10. | ALA121896 | 18n | T1/2 | = | 1.1 | hr | ALA622835 | hr | Rattus norvegicus | |||
11. | ALA121896 | 18n | Clearance | = | 43 | ml min-1 kg-1 | ALA621252 | mL.min-1.kg-1 | Rattus norvegicus | |||
12. | ALA121896 | 18n | Volume distribution | = | 4.7 | l kg-1 | ALA620195 | L.kg-1 | Rattus norvegicus | |||
13. | ALA121896 | 18n | IC50 | = | 37 | nM | ALA872976 | 7.43 | nM | Rattus norvegicus | ||
14. | ALA121896 | 18n | IC50 | = | 76 | nM | ALA796425 | 7.12 | nM | Rattus norvegicus | ||
15. | ALA121896 | 18n | logP | = | 2.78 | ALA636810 | ||||||
16. | ALA121896 | 18n | clogP | = | 3.18 | ALA625041 | ||||||
17. | ALA121896 | 18n | Ki | = | 3.4 | nM | ALA666465 | 8.47 | nM | Homo sapiens |